Author Gross, Oliver

1 to 50 of 56 Items

2006 | Journal Article
Bone marrow transplantation rescues Alport mice
Floege, J.; Kunter, U.; Weber, M. & Gross, O. (2006)
Nephrology Dialysis Transplantation, 21(10) pp. 2721-2723. DOI: https://doi.org/10.1093/ndt/gfl367
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2007 | Conference Abstract
Living donor kidney transplanation from relatives with mild urinary abnormalities in Alport syndrome: Risk, benefit and outcome in five families
Reinhardt, J.; Weber, M.; Mueller, G. A. & Gross, O. (2007)
Transplant International, 20
Oxford: Blackwell Publishing.
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2007 | Journal Article
Nephroprotective effect of the HMG-CoA-reductase inhibitor cerivastatin in a mouse model of progressive renal fibrosis in Alport syndrome
Koepke, M.-L.; Weber, M.; Schulze-Lohoff, E.; Beirowski, B.; Segerer, S. & Gross, O. (2007)
Nephrology Dialysis Transplantation, 22(4) pp. 1062-1069. DOI: https://doi.org/10.1093/ndt/gfl810
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2008 | Journal Article |
Inner ear defects and hearing loss in mice lacking the collagen receptor DDR1
zum Gottesberge, A. M. M.; Gross, O.; Becker-Lendzian, U.; Massing, T. & Vogel, W. F. (2008)
Laboratory Investigation, 88(1) pp. 27-37. DOI: https://doi.org/10.1038/labinvest.3700692
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2008 | Journal Article
Understanding renal disorders as systemic diseases: the fascinating world of basement membranes beyond the glomerulus
Gross, O. (2008)
Nephrology Dialysis Transplantation, 23(6) pp. 1823-1825. DOI: https://doi.org/10.1093/ndt/gfn129
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2009 | Journal Article
Treatment of Alport syndrome: beyond animal models
Gross, O. & Kashtan, C. E. (2009)
Kidney International, 76(6) pp. 599-603. DOI: https://doi.org/10.1038/ki.2009.223
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2009 | Conference Abstract
Mycophenolate Mofetil improves Kidney Function but not Survival in a COL4A3-deficient Mouse Model for Progressive Renal Fibrosis
Brandhorst, G.; Brehmer, F.; Petrova, D. T.; Gross, O.; Armstrong, V. W. & Oellerich, M. (2009)
Therapeutic Drug Monitoring, 31(5) 11th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Montreal, CANADA.
Philadelphia: Lippincott Williams & Wilkins.
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2009 | Journal Article
Stem cell therapy for Alport syndrome: the hope beyond the hype
Gross, O.; Borza, D.-B.; Anders, H.-J.; Licht, C.; Weber, M.; Segerer, S. & Torra, R. et al. (2009)
Nephrology Dialysis Transplantation, 24(3) pp. 731-734. DOI: https://doi.org/10.1093/ndt/gfn722
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2010 | Journal Article |
Integrin a2-deficient mice provide insights into specific functions of collagen receptors in the kidney
Girgert, R.; Martin, M.; Kruegel, J.; Miosge, N.; Temme, J.; Eckes, B. & Müller, G.-A. et al. (2010)
Fibrogenesis & Tissue Repair, 3(19)-10. DOI: https://doi.org/10.1186/1755-1536-3-19
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2010 | Journal Article
Mycophenolic Acid Displays IMPDH-Dependent and IMPDH-Independent Effects on Renal Fibroblast Proliferation and Function
Petrova, D. T.; Brandhorst, G.; Brehmer, F. ; Gross, O.; Oellerich, M. & Armstrong, V. W. (2010)
Therapeutic Drug Monitoring, 32(4) pp. 405-412. DOI: https://doi.org/10.1097/FTD.0b013e3181e44260
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2010 | Journal Article
Mycophenolic Acid Predose Concentrations and Renal Function in a Mouse Model for Progressive Renal Fibrosis
Brandhorst, G.; Brehmer, F.; Petrova, D. T; Gross, O.; Miosge, N.; Armstrong, V. W & Oellerich, M. (2010)
Therapeutic Drug Monitoring, 32(1) pp. 73-78. DOI: https://doi.org/10.1097/FTD.0b013e3181c91fc4
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2010 | Journal Article
Drug-Induced Granulomatous Interstitial Nephritis in a Patient With Ankylosing Spondylitis During Therapy With Adalimumab
Korsten, P. ; Sweiss, N. J.; Nagorsnik, U.; Niewold, T. B.; Groene, H.-J.; Gross, O. & Mueller, G. A. (2010)
American Journal of Kidney Diseases, 56(6) pp. E17-E21. DOI: https://doi.org/10.1053/j.ajkd.2010.08.019
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2010 | Journal Article
Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease
Gross, O.; Girgert, R.; Beirowski, B.; Kretzler, M.; Kang, H. G.; Kruegel, J. & Miosge, N. et al. (2010)
Matrix Biology, 29(5) pp. 346-356. DOI: https://doi.org/10.1016/j.matbio.2010.03.002
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2010 | Journal Article
Interstitial inflammation in Alport syndrome
Jedlicka, J.; Soleiman, A.; Draganovici, D.; Mandelbaum, J.; Ziegler, U.; Regele, H. & Wuethrich, R. P. et al. (2010)
Human Pathology, 41(4) pp. 582-593. DOI: https://doi.org/10.1016/j.humpath.2009.08.024
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2011 | Conference Abstract
Early therapy improves life expectancy in chronic renal failure: Data from the European ERA-EDTA dialysis registries and the European Alport therapy Register
Temme, J.; Kramer, A.; Peters, F.; Mueller, G.; Lange, K. & Gross, O. (2011)
Der Internist, 52(6) pp. 731-732.
New york: Springer.
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2011 | Journal Article |
Differential Kidney Proteome Profiling in a Murine Model of Renal Fibrosis under Treatment with Mycophenolate Mofetil
Petrova, D. T.; Brehmer, F.; Schultze, F. C.; Asif, A. R.; Gross, O.; Oellerich, M. & Brandhorst, G. (2011)
Pathobiology, 78(3) pp. 162-170. DOI: https://doi.org/10.1159/000324597
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2011 | Journal Article
Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-alpha-mediated podocyte loss
Ryu, M. I.; Kulkarni, O.; Radomska, E.; Miosge, N.; Gross, O. & Anders, H.-J. (2011)
Kidney International, 79(2) pp. 189-198. DOI: https://doi.org/10.1038/ki.2010.373
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2012 | Conference Abstract
EVALUATION OF EARLY DIAGNOSTIC MARKERS FOR ALPORT SYNDROME BEFORE THE ONSET OF MICROALBUMINURIA IN THE COL4A3-KNOCKOUT ANIMAL MODEL OF CHRONIC PROGRESSIVE RENAL FIBROSIS
Gross, O.; Diana, R.; Gry, D. H.; Asimal, B.; Johanna, T.; Imke, S.-E. & Lydia, W. et al. (2012)
Nephrology Dialysis Transplantation, 27 49th Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), Paris, FRANCE.
Oxford: Oxford Univ Press.
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2012 | Journal Article |
Safety and Efficacy of the ACE-Inhibitor Ramipril in Alport Syndrome: The Double-Blind, Randomized, Placebo-Controlled, Multicenter Phase III EARLY PRO-TECT Alport Trial in Pediatric Patients
Gross, O.; Friede, T.; Hilgers, R.; Görlitz, A.; Gavénis, K.; Ahmed, R. & Dürr, U. (2012)
ISRN Pediatrics, 2012 pp. 1-6. DOI: https://doi.org/10.5402/2012/436046
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2012 | Journal Article |
Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative
Kashtan, C.; Ding, J.; Gregory, M.; Gross, O.; Heidet, L.; Knebelmann, B. & Rheault, M. et al. (2012)
Pediatric Nephrology, 28(1) pp. 5-11. DOI: https://doi.org/10.1007/s00467-012-2138-4
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2012 | Journal Article
Incidence of renal failure and nephroprotection by RAAS inhibition in heterozygous carriers of X-chromosomal and autosomal recessive Alport mutations
Temme, J.; Peters, F.; Lange, K.; Pirson, Y.; Heidet, L.; Torra, R. & Grunfeld, J.-P. et al. (2012)
Kidney International, 81(8) pp. 779-783. DOI: https://doi.org/10.1038/ki.2011.452
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2012 | Journal Article
Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury
Ryu, M. I.; Migliorini, A.; Miosge, N.; Gross, O.; Shankland, S.; Brinkkoetter, P. T. & Hagmann, H. et al. (2012)
The Journal of Pathology, 228(4) pp. 482-494. DOI: https://doi.org/10.1002/path.4046
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2012 | Journal Article
Outcomes of Male Patients with Alport Syndrome Undergoing Renal Replacement Therapy
Temme, J.; Kramer, A.; Jager, K. J.; Lange, K.; Peters, F.; Mueller, G.-A. & Kramar, R. et al. (2012)
Clinical Journal of the American Society of Nephrology, 7(12) pp. 1969-1976. DOI: https://doi.org/10.2215/CJN.02190312
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2012 | Journal Article
Tumour necrosis factor-alpha drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis
Ryu, M. I.; Mulay, S. R.; Miosge, N.; Gross, O. & Anders, H.-J. (2012)
The Journal of Pathology, 226(1) pp. 120-131. DOI: https://doi.org/10.1002/path.2979
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2012 | Journal Article
Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy
Gross, O.; Licht, C.; Anders, H.-J.; Hoppe, B.; Beck, B.; Toenshoff, B. & Hoecker, B. et al. (2012)
Kidney International, 81(5) pp. 494-501. DOI: https://doi.org/10.1038/ki.2011.407
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2013 | Journal Article
Diagnosis of Alport syndrome-search for proteomic biomarkers in body fluids
Pohl, M.; Danz, K.; Gross, O.; John, U.; Urban, J.; Patzer, L. & Habbig, S. et al. (2013)
Pediatric Nephrology, 28(11) pp. 2117-2123. DOI: https://doi.org/10.1007/s00467-013-2533-5
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2013 | Journal Article
Discoidin Domain Receptor 1 Protein Is a Novel Modulator of Megakaryocyte-Collagen Interactions
Abbonante, V.; Gruppi, C.; Rubel, D.; Gross, O.; Moratti, R. & Balduini, A. (2013)
Journal of Biological Chemistry, 288(23) pp. 16738-16746. DOI: https://doi.org/10.1074/jbc.M112.431528
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2013 | Review
Alport syndrome-insights from basic and clinical research
Kruegel, J.; Rubel, D.& Gross, O. (2013)
Nature Reviews Nephrology, 9(3) pp. 170-178.
Nature Publishing Group. DOI: https://doi.org/10.1038/nrneph.2012.259
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2014 | Conference Abstract
PDGF-C MEDIATES HYPERTENSION AND RENAL FIBROSIS IN MICE
van Roeyen, C. R. C.; Drescher, A.; Hess, K.; Boor, P.; Martin, I. V.; Zok, S. & Braun, G. et al. (2014)
Nephrology Dialysis Transplantation, 29 51st Congress of the European-Renal-Association(ERA)/European-Dialysis-and-Transplant-Associa tion (EDTA), Amsterdam, NETHERLANDS.
Oxford: Oxford Univ Press.
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2014 | Journal Article
Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice
Rubel, D.; Frese, J.; Martin, M.; Leibnitz, A.; Girgert, R.; Miosge, N. & Eckes, B. et al. (2014)
Matrix Biology, 34 pp. 13-21. DOI: https://doi.org/10.1016/j.matbio.2014.01.006
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2014 | Journal Article | Letter Note
Challenges for Academic Investigator-Initiated Pediatric Trials for Rare Diseases
Ahmed, R.; Duerr, U.; Gavenis, K.; Hilgers, R. & Gross, O. (2014)
Clinical Therapeutics, 36(2) pp. 184-190. DOI: https://doi.org/10.1016/j.clinthera.2014.01.013
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2014 | Journal Article |
Effects of mycophenolate mofetil on kidney function and phosphorylation status of renal proteins in Alport COL4A3-deficient mice
Petrova, D. T.; Schultze, F. C.; Brandhorst, G.; Luchs, K.-D.; Lenz, C.; Urlaub, H. & Rubel, D. et al. (2014)
Proteome Science, 12 art. 56. DOI: https://doi.org/10.1186/s12953-014-0056-z
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2014 | Journal Article |
The 2014 International Workshop on Alport Syndrome.
Miner, J. H.; Baigent, C.; Flinter, F.; Gross, O.; Judge, P.; Kashtan, C. E. & Lagas, S. et al. (2014)
Kidney international, 86(4) pp. 679-684. DOI: https://doi.org/10.1038/ki.2014.229
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2015 | Journal Article |
Intensive Supportive Care plus Immunosuppression in IgA Nephropathy
Rauen, T.; Eitner, F.; Fitzner, C.; Sommerer, C.; Zeier, M.; Otte, B. & Panzer, U. et al. (2015)
New England Journal of Medicine, 373(23) pp. 2225-2236. DOI: https://doi.org/10.1056/NEJMoa1415463
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2015 | Journal Article
Preclinical Alterations in the Serum of COL(IV)A3(-)/(-) Mice as Early Biomarkers of Alport Syndrome
Muckova, P.; Wendler, S.; Rubel, D.; Buechler, R.; Alert, M.; Gross, O. & Rhode, H. (2015)
Journal of Proteome Research, 14(12) pp. 5202-5214. DOI: https://doi.org/10.1021/acs.jproteome.5b00814
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2016 | Conference Abstract
POTENTIAL OF RAAS-BLOCKADE TO DELAY RENAL DISEASE IN PATIENTS WITH ALPORT SYNDROME: A 4-YEAR PROSPECTIVE STUDY
Stock, J. ; Glonke, N.; Sonntag, J. ; Kuenanz, J. & Gross, O. (2016)
Nephrology Dialysis Transplantation, 31 53rd ERA-EDTA Congress, Vienna, AUSTRIA.
Oxford: Oxford Univ Press.
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2017 | Review
Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome
Gross, O.; Kashtan, C. E.; Rheault, M. N.; Flinter, F.; Savige, J.; Miner, J. H.& Torra, R. et al. (2017)
Nephrology Dialysis Transplantation, 32(6) pp. 916-924.
Oxford Univ Press. DOI: https://doi.org/10.1093/ndt/gfw095
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2017 | Journal Article
Prospective study on the potential of RAAS blockade to halt renal disease in Alport syndrome patients with heterozygous mutations
Stock, J.; Kuenanz, J.; Glonke, N.; Sonntag, J.; Frese, J.; Toenshoff, B. & Hoecker, B. et al. (2017)
Pediatric Nephrology, 32(1) pp. 131-137. DOI: https://doi.org/10.1007/s00467-016-3452-z
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2019 | Journal Article |
Genetische Ursachen und Therapie beim Alport-Syndrom
Gross, O. & Hoefele, J. (2019)
Medizinische Genetik,(4) pp. 429-437. DOI: https://doi.org/10.1007/s11825-018-0214-2
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2019 | Journal Article | Research Paper |
Kidney Injury by Variants in the COL4A5 Gene Aggravated by Polymorphisms in Slit Diaphragm Genes Causes Focal Segmental Glomerulosclerosis.
Frese, J.; Kettwig, M.; Zappel, H.; Hofer, J.; Gröne, H.-J.; Nagel, M. & Sunder-Plassmann, G. et al. (2019)
International Journal of Molecular Sciences, 20(3) art. 519. DOI: https://doi.org/10.3390/ijms20030519
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2019 | Journal Article |
The importance of clinician, patient and researcher collaborations in Alport syndrome
Rheault, M. N.; Savige, J.; Randles, M. J.; Weinstock, A.; Stepney, M.; Turner, A N. & Parziale, G. et al. (2019)
Pediatric Nephrology, pp. 1-10. DOI: https://doi.org/10.1007/s00467-019-04241-7
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2020 | Journal Article
A multicenter, randomized, placebo-controlled, double-blind phase 3 trial with open-arm comparison indicates safety and efficacy of nephroprotective therapy with ramipril in children with Alport’s syndrome
Gross, O.; Tönshoff, B.; Weber, L. T.; Pape, L.; Latta, K.; Fehrenbach, H. & Lange-Sperandio, B. et al. (2020)
Kidney International, 97(6) pp. 1275-1286. DOI: https://doi.org/10.1016/j.kint.2019.12.015
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2020 | Journal Article
COVID-19 und die Niere – Klinik
Gross, O. (2020)
Der Nephrologe, 16(1) pp. 26-32. DOI: https://doi.org/10.1007/s11560-020-00470-2
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2021 | Journal Article |
Case Report: Eculizumab and ECMO Rescue Therapy of Severe ARDS in Goodpasture Syndrome
Sobotta, M.; Moerer, O. & Gross, O. (2021)
Frontiers in Medicine, 8. DOI: https://doi.org/10.3389/fmed.2021.720949
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2021 | Journal Article
Update zu: COVID-19 und die Niere – Klinik
Böckhaus, J.; Plüß, M.; Tampe, B. & Gross, O. (2021)
Der Nephrologe, 16(5) pp. 314-318. DOI: https://doi.org/10.1007/s11560-021-00530-1
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2021 | Journal Article
Potenzieller Podozytenschaden durch Bardoxolone in klinischen Studien
Gross, O. (2021)
Der Nephrologe, 17(1) pp. 57-58. DOI: https://doi.org/10.1007/s11560-021-00548-5
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2021 | Journal Article
Neuer Therapieansatz für Podozytopathien
Gross, O. (2021)
Die Nephrologie, 17(4) pp. 259-260. DOI: https://doi.org/10.1007/s11560-021-00549-4
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2021 | Journal Article | Overview |
Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues
Begemann, M.; Gross, O.; Wincewicz, D.; Hardeland, R.; Daguano Gastaldi, V.; Vieta, E. & Weissenborn, K. et al. (2021)
Molecular Medicine, 27(1) art. 120. DOI: https://doi.org/10.1186/s10020-021-00381-5
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2022 | Journal Article
Lifelong effect of therapy in young patients with the COL4A5 Alport missense variant p.(Gly624Asp): a prospective cohort study
Boeckhaus, J.; Hoefele, J.; Riedhammer, K. M; Nagel, M.; Beck, B. B; Choi, M. & Gollasch, M. et al. (2022)
Nephrology Dialysis Transplantation, art. gfac006. DOI: https://doi.org/10.1093/ndt/gfac006
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2022 | Journal Article | Research Paper |
Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models
Rubel, D.; Boulanger, J.; Craciun, F.; Xu, E. Y.; Zhang, Y.; Phillips, L. & Callahan, M. et al. (2022)
Cells, 11(4). DOI: https://doi.org/10.3390/cells11040594
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