Author Becker, Stefan
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2004 | Journal Article
Crystallization and preliminary crystallographic studies of the NCoA-1/SRC-1 PAS-B domain bound to the L XX LL motif of the STAT6 transactivation domain
Razeto, A.; Pfitzner, E. & Becker, S. (2004)
Acta Crystallographica Section D Biological Crystallography, 60(3) pp. 550-552. DOI: https://doi.org/10.1107/S0907444903029378
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2006 | Journal Article
MPI-DING reference glasses for in situ microanalysis: New reference values for element concentrations and isotope ratios
Jochum, K. P.; Stoll, B.; Herwig, K.; Willbold, M. ; Hofmann, A. W.; Amini, M. & Aarburg, S. et al. (2006)
Geochemistry, Geophysics, Geosystems, 7(2). DOI: https://doi.org/10.1029/2005GC001060
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2007 | Journal Article
The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A
Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M. & Becker, S. (2007)
Journal of Biological Chemistry, 282(7) pp. 5015-5025. DOI: https://doi.org/10.1074/jbc.M606746200
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2008 | Journal Article
Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: A flexible flap subdomain controls access to the catalytic site
Schlicker, C.; Fokina, O.; Kioft, N.; Gruene, T.; Becker, S.; Sheldrick, G. M. & Forchhammer, K. (2008)
Journal of Molecular Biology, 376(2) pp. 570-581. DOI: https://doi.org/10.1016/j.jmb.2007.11.097
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2009 | Journal Article
Crystallographic ab initio protein structure solution below atomic resolution
Rodriguez, D. D.; Grosse, C. ; Himmel, S.; Gonzalez, C.; de Ilarduya, I. M.; Becker, S. & Sheldrick, G. M. et al. (2009)
Nature Methods, 6(9) pp. 651-U39. DOI: https://doi.org/10.1038/NMETH.1365
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2010 | Journal Article
Molten Globule Precursor States Are Conformationally Correlated to Amyloid Fibrils of Human β-2-Microglobulin
Skora, L.; Becker, S. & Zweckstetter, M. (2010)
Journal of the American Chemical Society, 132(27) pp. 9223-9225. DOI: https://doi.org/10.1021/ja100453e
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2011 | Journal Article
Conserved core of amyloid fibrils of wild type and A30P mutant α-synuclein
Cho, M.-K.; Kim, H.-Y.; Fernandez, C. O.; Becker, S. & Zweckstetter, M. (2011)
Protein Science, 20(2) pp. 387-395. DOI: https://doi.org/10.1002/pro.570
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2011 | Journal Article |
Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy
Gruene, T.; Cho, M.-K.; Karyagina, I.; Kim, H.-Y.; Grosse, C.; Giller, K. & Zweckstetter, M. et al. (2011)
Journal of Biomolecular NMR, 49(2) pp. 111-119. DOI: https://doi.org/10.1007/s10858-011-9471-y
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2012 | Journal Article
Structural Comparison of Mouse and Human α-Synuclein Amyloid Fibrils by Solid-State NMR
Lv, G.; Kumar, A.; Giller, K.; Orcellet, M. L.; Riedel, D.; Fernández, C. O. & Becker, S. et al. (2012)
Journal of Molecular Biology, 420(1-2) pp. 99-111. DOI: https://doi.org/10.1016/j.jmb.2012.04.009
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2012 | Journal Article
Structure of the RBD-PRDI fragment of the antiterminator protein GlcT
Himmel, S.; Grosse, C.; Wolff, S.; Schwiegk, C. & Becker, S. (2012)
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 68 pp. 751-756. DOI: https://doi.org/10.1107/S1744309112020635
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2013 | Journal Article
Burial of the Polymorphic Residue 129 in Amyloid Fibrils of Prion Stop Mutants
Skora, L.; Fonseca-Ornelas, L.; Hofele, R. V.; Riedel, D.; Giller, K.; Watzlawik, J. & Schulz-Schaeffer, W. J. et al. (2013)
Journal of Biological Chemistry, 288(5) pp. 2994-3002. DOI: https://doi.org/10.1074/jbc.M112.423715
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2014 | Journal Article
Turn Plasticity Distinguishes Different Modes of Amyloid-beta Aggregation
Rezaei-Ghaleh, N.; Amininasab, M.; Giller, K.; Kumar, S.; Stuendl, A.; Schneider, A. & Becker, S. et al. (2014)
Journal of the American Chemical Society, 136(13) pp. 4913-4919. DOI: https://doi.org/10.1021/ja411707y
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2014 | Journal Article |
Small molecule-mediated stabilization of vesicle-associated helical alpha-synuclein inhibits pathogenic misfolding and aggregation
Fonseca-Ornelas, L.; Eisbach, S. E.; Paulat, M.; Giller, K.; Fernandez, C. O.; Outeiro, T. F. & Becker, S. et al. (2014)
Nature Communications, 5 art. 5857. DOI: https://doi.org/10.1038/ncomms6857
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2014 | Journal Article
Molecular Basis of the Dynamic Structure of the TIM23 Complex in the Mitochondrial Intermembrane Space
Bajaj, R.; Jaremko, L.; Jaremko, M.; Becker, S. & Zweckstetter, M. (2014)
Structure, 22(10) pp. 1501-1511. DOI: https://doi.org/10.1016/j.str.2014.07.015
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2014 | Journal Article
Interaction of the Intermembrane Space Domain of Tim23 Protein with Mitochondrial Membranes
Bajaj, R.; Munari, F.; Becker, S. & Zweckstetter, M. (2014)
Journal of Biological Chemistry, 289(50) pp. 34620-34626. DOI: https://doi.org/10.1074/jbc.M114.595702
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2014 | Journal Article
Toward the functional oligomerization state of tryptophan-rich sensory proteins
Jaremko, L.; Jaremko, M.; Becker, S. & Zweckstetter, M. (2014)
Protein Science, 23(8) pp. 1154-1160. DOI: https://doi.org/10.1002/pro.2487
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2014 | Journal Article
Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex
Wysoczanki, P.; Schneider, C.; Xiang, S.; Munari, F.; Trowitzsch, S.; Wahl, M. C. & Luehrmann, R. et al. (2014)
Nature Structural & Molecular Biology, 21(10) pp. 911-918. DOI: https://doi.org/10.1038/nsmb.2889
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2014 | Journal Article |
NMR-Based Detection of Hydrogen/Deuterium Exchange in Liposome-Embedded Membrane Proteins
Yao, X.; Duerr, U. H. N.; Gattin, Z.; Laukat, Y.; Narayanan, R. L.; Brueckner, A.-K. & Meisinger, C. et al. (2014)
PLoS ONE, 9(11) art. e112374. DOI: https://doi.org/10.1371/journal.pone.0112374
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2014 | Journal Article
A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins
Yao, X.; Becker, S. & Zweckstetter, M. (2014)
Journal of Biomolecular NMR, 60(4) pp. 231-240. DOI: https://doi.org/10.1007/s10858-014-9872-9
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2014 | Journal Article
Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand
Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S. & Zweckstetter, M. (2014)
Science, 343(6177) pp. 1363-1366. DOI: https://doi.org/10.1126/science.1248725
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2015 | Journal Article
Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization
Chevelkov, V.; Xiang, S.; Giller, K.; Becker, S.; Lange, A. & Reif, B. (2015)
Journal of Biomolecular NMR, 61(2) pp. 151-160. DOI: https://doi.org/10.1007/s10858-015-9902-2
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2015 | Journal Article |
Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric alpha-Synuclein and Reduce Its Aggregation in Cells
Moree, B.; Yin, G.; Lazaro, D. F.; Munari, F.; Strohaeker, T.; Giller, K. & Becker, S. et al. (2015)
Journal of Biological Chemistry, 290(46) pp. 27582-27593. DOI: https://doi.org/10.1074/jbc.M114.636027
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2015 | Journal Article
Structure of the mammalian TSPO/PBR protein
Jaremko, M.; Jaremko, L.; Jaipuria, G.; Becker, S. & Zweckstetter, M. (2015)
Biochemical Society Transactions, 43 pp. 566-571. DOI: https://doi.org/10.1042/BST20150029
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2015 | Journal Article
Multiple Paramagnetic Effects through a Tagged Reporter Protein
Camacho-Zarco, A. R.; Munari, F.; Wegstroth, M.; Liu, W.-M.; Ubbink, M.; Becker, S. & Zweckstetter, M. (2015)
Angewandte Chemie International Edition, 54(1) pp. 336-339. DOI: https://doi.org/10.1002/anie.201408615
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2015 | Journal Article
Structural Integrity of the A147T Polymorph of Mammalian TSPO
Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S. & Zweckstetter, M. (2015)
ChemBioChem, 16(10) pp. 1483-1489. DOI: https://doi.org/10.1002/cbic.201500217
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2015 | Journal Article |
Structures of intermediates during RES complex assembly
Wysoczanski, P.; Becker, S. & Zweckstetter, M. (2015)
Scientific Reports, 5 art. 12545. DOI: https://doi.org/10.1038/srep12545
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2015 | Journal Article
Conformational Flexibility in the Transmembrane Protein TSPO
Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S. & Zweckstetter, M. (2015)
Chemistry - A European Journal, 21(46) pp. 16555-16563. DOI: https://doi.org/10.1002/chem.201502314
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2015 | Journal Article
Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli
Habenstein, B. ; Loquet, A.; Hwang, S.; Giller, K. ; Vasa, S. K.; Becker, S. & Habeck, M. et al. (2015)
Angewandte Chemie International Edition, 54(40) pp. 11691-11695. DOI: https://doi.org/10.1002/anie.201505065
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2016 | Journal Article
Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand
Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S. & Zweckstetter, M. (2016)
Biomolecular NMR Assignments, 10(1) pp. 79-83. DOI: https://doi.org/10.1007/s12104-015-9642-y
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2017 | Journal Article |
Human cyclophilin 40 unravels neurotoxic amyloids
Baker, J. D.; Shelton, L. B.; Zheng, D.; Favretto, F.; Nordhues, B. A.; Darling, A. & Sullivan, L. E. et al. (2017)
PLoS Biology, 15(6) art. e2001336. DOI: https://doi.org/10.1371/journal.pbio.2001336
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2017 | Journal Article |
Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure
Jaipuria, G.; Leonov, A.; Giller, K.; Vasa, S. K.; Jaremko, L.; Jaremko, M. & Linser, R. et al. (2017)
Nature Communications, 8 art. 14893. DOI: https://doi.org/10.1038/ncomms14893
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2017 | Journal Article |
The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease
de Oliveira, R. M.; Miranda, H. V.; Francelle, L.; Pinho, R.; Szegoe, E. M.; Martinho, R. & Munari, F. et al. (2017)
PLoS Biology, 15(3) art. e2000374. DOI: https://doi.org/10.1371/journal.pbio.2000374
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2018 | Journal Article
The Small Molecule anle138b Shows Interaction with α-Synuclein Oligomers in Phospholipid Membranes
Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al. (2018)
Biophysical Journal, 114(3) pp. 560a. DOI: https://doi.org/10.1016/j.bpj.2017.11.3064
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2018 | Journal Article
Structure of a green fluorescent protein biosensor – implications for FRET
Becker, S.; Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O. & Griesinger, C. (2018)
Acta Crystallographica Section A Foundations and Advances, 74(a1) pp. a95-a95. DOI: https://doi.org/10.1107/S010876731809904X
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2018 | Journal Article |
Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity
Tolö, J.; Taschenberger, G.; Leite, K.; Stahlberg, M. A.; Spehlbrink, G.; Kues, J. & Munari, F. et al. (2018)
Frontiers in Molecular Neuroscience, 11 art. 49. DOI: https://doi.org/10.3389/fnmol.2018.00049
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2019 | Journal Article
Protein-Drug Interactions in the Membrane: The Small Molecule Anle138b and its Binding to α-Synuclein Oligomers
Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al. (2019)
Biophysical Journal, 116(3) pp. 352a. DOI: https://doi.org/10.1016/j.bpj.2018.11.1913
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2019 | Journal Article
Dynamic tuning of FRET in a green fluorescent protein biosensor
Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O.; Griesinger, C. & Becker, S. (2019)
Science Advances, 5(8). DOI: https://doi.org/10.1126/sciadv.aaw4988
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2019 | Journal Article | Research Paper
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein
Pinho, R.; Paiva, I.; Jercic, K. G.; Fonseca-Ornelas, L.; Gerhardt, E.; Fahlbusch, C. & Garcia-Esparcia, P. et al. (2019)
Human Molecular Genetics, 28(1) pp. 31-50. DOI: https://doi.org/10.1093/hmg/ddy326
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2021 | Journal Article
Early Divergence in Misfolding Pathways of Amyloid‐Beta Peptides
Mamone, S.; Glöggler, S.; Becker, S. & Rezaei‐Ghaleh, N. (2021)
ChemPhysChem, art. cphc.202100542. DOI: https://doi.org/10.1002/cphc.202100542
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2021 | Journal Article
Combined High-Pressure and Multiquantum NMR and Molecular Simulation Propose a Role for N-Terminal Salt Bridges in Amyloid-Beta
Vemulapalli, S. P. B.; Becker, S.; Griesinger, C. & Rezaei-Ghaleh, N. (2021)
The Journal of Physical Chemistry Letters, 12(40) pp. 9933-9939. DOI: https://doi.org/10.1021/acs.jpclett.1c02595
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2021 | Journal Article
Backbone Torsion Angle Determination Using Proton Detected Magic-Angle Spinning Nuclear Magnetic Resonance
Xue, K.; Nimerovsky, E.; Tekwani Movellan, K. A.; Becker, S. & Andreas, L. B. (2021)
The Journal of Physical Chemistry Letters, pp. 18-24. DOI: https://doi.org/10.1021/acs.jpclett.1c03267
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2021 | Journal Article |
Proton Detected Solid-State NMR of Membrane Proteins at 28 Tesla (1.2 GHz) and 100 kHz Magic-Angle Spinning
Nimerovsky, E.; Movellan, K. T.; Zhang, X. C.; Forster, M. C.; Najbauer, E.; Xue, K. & Dervişoǧlu, R. et al. (2021)
Biomolecules, 11(5) pp. 752. DOI: https://doi.org/10.3390/biom11050752
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2021 | Journal Article |
Towards a native environment: structure and function of membrane proteins in lipid bilayers by NMR
Xue, K.; Movellan, K. T.; Zhang, X. C.; Najbauer, E. E.; Forster, M. C.; Becker, S. & Andreas, L. B. (2021)
Chemical Science, 12(43) pp. 14332-14342. DOI: https://doi.org/10.1039/D1SC02813H
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2021 | Journal Article | Research Paper |
Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils
Tatenhorst, L.; Caldi Gomes, L.; Zhang, S.; Parvaz, M.; Carboni, E.; Roser, A. & El DeBakey, H. et al. (2021)
Journal of Neurochemistry, 159(3) art. jnc.15461. DOI: https://doi.org/10.1111/jnc.15461
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2021 | Journal Article |
Structure, gating and interactions of the voltage-dependent anion channel
Najbauer, E. E.; Becker, S.; Giller, K.; Zweckstetter, M.; Lange, A.; Steinem, C. & de Groot, B. L. et al. (2021)
European Biophysics Journal, 50(2) pp. 159-172. DOI: https://doi.org/10.1007/s00249-021-01515-7
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2022 | Journal Article
The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro
Nedaei, H.; Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Karami, L.; Moosavi-Movahedi, A. A. & Griesinger, C. et al. (2022)
Journal of Biological Chemistry, 298(3) art. S0021925822001028. DOI: https://doi.org/10.1016/j.jbc.2022.101662
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2022 | Journal Article
Direct Detection of Bound Ammonium Ions in the Selectivity Filter of Ion Channels by Solid-State NMR
Öster, C.; Tekwani Movellan, K.; Goold, B.; Hendriks, K.; Lange, S.; Becker, S. & de Groot, B. L. et al. (2022)
Journal of the American Chemical Society, 144(9) pp. 4147-4157. DOI: https://doi.org/10.1021/jacs.1c13247
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2022 | Journal Article
Molecular Basis of Small-Molecule Binding to α-Synuclein
Robustelli, P.; Ibanez-de-Opakua, A.; Campbell-Bezat, C.; Giordanetto, F.; Becker, S.; Zweckstetter, M. & Pan, A. C. et al. (2022)
Journal of the American Chemical Society, 144(6) pp. 2501-2510. DOI: https://doi.org/10.1021/jacs.1c07591
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2022 | Journal Article
Modest Offset Difference Internuclear Selective Transfer via Homonuclear Dipolar Coupling
Nimerovsky, E.; Najbauer, E. E.; Movellan, K. T.; Xue, K.; Becker, S. & Andreas, L. B. (2022)
The Journal of Physical Chemistry Letters, 13(6) pp. 1540-1546. DOI: https://doi.org/10.1021/acs.jpclett.1c03871
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2022 | Journal Article
Structure and Gating Behavior of the Human Integral Membrane Protein VDAC1 in a Lipid Bilayer
Najbauer, E. E.; Tekwani Movellan, K.; Giller, K.; Benz, R.; Becker, S.; Griesinger, C. & Andreas, L. B. (2022)
Journal of the American Chemical Society, 144(7) pp. 2953-2967. DOI: https://doi.org/10.1021/jacs.1c09848
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