Author Nau, R.

• 2002 | Review
  ​ ​Modulation of release of proinflammatory bacterial compounds by antibacterials: Potential impact on course of inflammation and outcome in sepsis and meningitis​
  Nau, R.& Eiffert, H.​ (2002)
  Clinical Microbiology Reviews, 15​(1) pp. 95​-+​.​
  Amer Soc Microbiology. DOI: https://doi.org/10.1128/CMR.15.1.95-110.2002 
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• 2002 | Review
  ​ ​Neuronal injury in bacterial meningitis: mechanisms and implications for therapy​
  Nau, R.& Bruck, W. W.​ (2002)
  Trends in Neurosciences, 25​(1) pp. 38​-45​.​
  Elsevier Science London. DOI: https://doi.org/10.1016/S0166-2236(00)02024-5 
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• 2002 | Journal Article
  ​ ​Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis​
  Wellmer, A.; Zysk, G.; Gerber, J.; Kunst, T.; von Mering, M.; Bunkowski, S. & Eiffert, H. et al.​ (2002) 
  Infection and Immunity, 70(11) pp. 6504​-6508​.​ DOI: https://doi.org/10.1128/IAI.70.11.6504-6508.2002 
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• 2003 | Journal Article | Letter Note
  ​ ​Pathophysiology of neuronal injury in bacterial meningitis: concepts and implications​
  Nau, R.​ (2003) 
  Neurología, 18(2) pp. 47​-53​.​
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• 2003 | Journal Article
  ​ ​Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9)​
  Iliev, A. I.; Stringaris, A. K.; Nau, R. & Neumann, H.​ (2003) 
  The FASEB Journal, 17(15) pp. 412​-+​.​ DOI: https://doi.org/10.1096/fj.03-0670fje 
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• 2003 | Journal Article
  ​ ​Polyneuropathy as a sole syndrome in mialignant thymoma​
  Schmidt, H.; Kaboth, U.; Brinck, U.; Ratzka, P.; Rustenbeck, H. H. & Nau, R.​ (2003) 
  Der Nervenarzt, 74(10) pp. 888​-+​.​ DOI: https://doi.org/10.1007/s00115-003-1552-z 
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• 2003 | Journal Article
  ​ ​Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia​
  Michel, U.; Gerber, J.; O'Connor, A. E.; Bunkowski, S.; Bruck, W. W.; Nau, R. & Phillips, D. J.​ (2003) 
  Journal of Neurochemistry, 86(1) pp. 238​-245​.​ DOI: https://doi.org/10.1046/j.1471-4159.2003.01834.x 
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• 2003 | Conference Paper
  ​ ​Regional differences in glutamine synthetase inhibition by L-methionine sulfoximine: a microdialysis study in the rabbit brain​
  Bottcher, T.; Goiny, M.; Bering, J.; Domhof, S.; Nau, R. & Ungerstedt, U.​ (2003)
  Experimental Brain Research, 150(2) pp. 194​-200. ​12th Meeting of the European-Neurological-Society (ENS)​, BERLIN, GERMANY.
  New york​: Springer. DOI: https://doi.org/10.1007/s00221-003-1401-0 
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• 2003 | Journal Article
  ​ ​Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone​
  Spreer, A.; Kerstan, H.; Bottcher, T.; Gerber, J.; Siemer, A.; Zysk, G. & Mitchell, T. J. et al.​ (2003) 
  Antimicrobial Agents and Chemotherapy, 47(8) pp. 2649​-2654​.​ DOI: https://doi.org/10.1128/AAC.47.8.2649-2654.2003 
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• 2003 | Journal Article
  ​ ​Rifampin followed by ceftriaxone for experimental meningitis decreases lipoteichoic acid concentrations in cerebrospinal fluid and reduces neuronal damage in comparison to ceftriaxone alone​
  Gerber, J.; Pohl, K.; Sander, V.; Bunkowski, S. & Nau, R.​ (2003) 
  Antimicrobial Agents and Chemotherapy, 47(4) pp. 1313​-1317​.​ DOI: https://doi.org/10.1128/AAC.47.4.1313-1317.2003 
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• 2003 | Journal Article
  ​ ​Increased neurogenesis after experimental Streptococcus pneumoniae meningitis​
  Gerber, J.; Bottcher, T.; Bering, J.; Bunkowski, S.; Bruck, W. W.; Kuhnt, U. & Nau, R.​ (2003) 
  Journal of Neuroscience Research, 73(4) pp. 441​-446​.​ DOI: https://doi.org/10.1002/jnr.10682 
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• 2003 | Journal Article
  ​ ​Serum concentrations of activin and follistatin are elevated and run in parallel in patients with septicemia​
  Michel, U.; Ebert, S.; Phillips, D. & Nau, R.​ (2003) 
  European Journal of Endocrinology, 148(5) pp. 559​-564​.​ DOI: https://doi.org/10.1530/eje.0.1480559 
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• 2003 | Journal Article
  ​ ​Matrix metalloproteinase-9 deficiency impairs host defense mechanisms against Streptococcus pneumoniae in a mouse model of bacterial meningitis​
  Bottcher, T.; Spreer, A.; Azeh, I.; Nau, R. & Gerber, J.​ (2003) 
  Neuroscience Letters, 338(3) pp. 201​-204​.​ DOI: https://doi.org/10.1016/S0304-3940(02)01406-4 
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• 2003 | Journal Article
  ​ ​Differential regulation of Toll-like receptor mRNAs in experimental murine central nervous system infections​
  Bottcher, T.; von Mering, M.; Ebert, S.; Meyding-Lamade, U.; Kuhnt, U.; Gerber, J. & Nau, R.​ (2003) 
  Neuroscience Letters, 344(1) pp. 17​-20​.​ DOI: https://doi.org/10.1016/S0304-3940(03)00404-X 
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• 2003 | Journal Article
  ​ ​Deep cerebral venous sinus thrombosis often presents with neuropsychologic symptoms​
  von Mering, M.; Stiefel, M.; Brockmann, K. & Nau, R.​ (2003) 
  Journal of Clinical Neuroscience, 10(3) pp. 310​-312​.​ DOI: https://doi.org/10.1016/S0967-5868(03)00017-1 
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• 2004 | Review
  ​ ​Therapy of bacterial meningitis​
  Schmidt, H.& Nau, R.​ (2004)
  AKTUELLE NEUROLOGIE, 31​(5) pp. 231​-240​.​
  Georg Thieme Verlag Kg. DOI: https://doi.org/10.1055/s-2003-814936 
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• 2004 | Conference Abstract
  ​ ​PavA of Streptococcus pneumoniae: a modulator of invasion and meningeal inflammation​
  Pracht, D.; Elm, C.; Gerber, J.; Jenkinson, H. F.; Nau, R. & Hammerschmidt, S.​ (2004)
  International Journal of Medical Microbiology, 294 pp. 87​-88. ​Annual Meeting of the DGHM​, Munster, GERMANY.
  Jena​: Urban & Fischer Verlag.
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• 2004 | Journal Article
  ​ ​Axonal injury, a neglected cause of CNS damage in bacterial meningitis​
  Nau, R.; Gerber, J.; Bunkowski, S. & Bruck, W. W.​ (2004) 
  Neurology, 62(3) pp. 509​-511​.​
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• 2004 | Journal Article
  ​ ​Increased mortality and spatial memory deficits in TNF-alpha-deficient mice in ceftriaxone-treated experimental pneumococcal meningitis​
  Gerber, J.; Bottcher, T.; Hahn, M.; Siemer, A.; Bunkowski, S. & Nau, R.​ (2004) 
  Neurobiology of Disease, 16(1) pp. 133​-138​.​ DOI: https://doi.org/10.1016/j.nbd.2004.01.013 
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• 2004 | Journal Article
  ​ ​Differences in clinical manifestation of Streptococcus pneumoniae infection are not correlated with in vitro production and release of the virulence factors pneumolysin and lipoteichoic and teichoic acids​
  Spreer, A.; Lis, A.; Gerber, J.; Reinert, R. R.; Eiffert, H. & Nau, R.​ (2004) 
  Journal of Clinical Microbiology, 42(7) pp. 3342​-3345​.​ DOI: https://doi.org/10.1128/JCM.42.7.3342-3345.2004 
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