Author Gross, Oliver

• 2012 | Journal Article
  ​ ​Incidence of renal failure and nephroprotection by RAAS inhibition in heterozygous carriers of X-chromosomal and autosomal recessive Alport mutations​
  Temme, J.; Peters, F.; Lange, K.; Pirson, Y.; Heidet, L.; Torra, R. & Grunfeld, J.-P. et al.​ (2012) 
  Kidney International, 81(8) pp. 779​-783​.​ DOI: https://doi.org/10.1038/ki.2011.452 
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• 2012 | Journal Article
  ​ ​Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury​
  Ryu, M. I.; Migliorini, A.; Miosge, N.; Gross, O.; Shankland, S.; Brinkkoetter, P. T. & Hagmann, H. et al.​ (2012) 
  The Journal of Pathology, 228(4) pp. 482​-494​.​ DOI: https://doi.org/10.1002/path.4046 
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• 2012 | Journal Article
  ​ ​Outcomes of Male Patients with Alport Syndrome Undergoing Renal Replacement Therapy​
  Temme, J.; Kramer, A.; Jager, K. J.; Lange, K.; Peters, F.; Mueller, G.-A. & Kramar, R. et al.​ (2012) 
  Clinical Journal of the American Society of Nephrology, 7(12) pp. 1969​-1976​.​ DOI: https://doi.org/10.2215/CJN.02190312 
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• 2012 | Journal Article
  ​ ​Tumour necrosis factor-alpha drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis​
  Ryu, M. I.; Mulay, S. R.; Miosge, N.; Gross, O. & Anders, H.-J.​ (2012) 
  The Journal of Pathology, 226(1) pp. 120​-131​.​ DOI: https://doi.org/10.1002/path.2979 
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• 2012 | Journal Article
  ​ ​Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy​
  Gross, O.; Licht, C.; Anders, H.-J.; Hoppe, B.; Beck, B.; Toenshoff, B. & Hoecker, B. et al.​ (2012) 
  Kidney International, 81(5) pp. 494​-501​.​ DOI: https://doi.org/10.1038/ki.2011.407 
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• 2013 | Journal Article
  ​ ​Diagnosis of Alport syndrome-search for proteomic biomarkers in body fluids​
  Pohl, M.; Danz, K.; Gross, O.; John, U.; Urban, J.; Patzer, L. & Habbig, S. et al.​ (2013) 
  Pediatric Nephrology, 28(11) pp. 2117​-2123​.​ DOI: https://doi.org/10.1007/s00467-013-2533-5 
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• 2013 | Journal Article
  ​ ​Discoidin Domain Receptor 1 Protein Is a Novel Modulator of Megakaryocyte-Collagen Interactions​
  Abbonante, V.; Gruppi, C.; Rubel, D.; Gross, O.; Moratti, R. & Balduini, A.​ (2013) 
  Journal of Biological Chemistry, 288(23) pp. 16738​-16746​.​ DOI: https://doi.org/10.1074/jbc.M112.431528 
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• 2013 | Review
  ​ ​Alport syndrome-insights from basic and clinical research​
  Kruegel, J.; Rubel, D.& Gross, O.​ (2013)
  Nature Reviews Nephrology, 9​(3) pp. 170​-178​.​
  Nature Publishing Group. DOI: https://doi.org/10.1038/nrneph.2012.259 
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• 2014 | Conference Abstract
  ​ ​PDGF-C MEDIATES HYPERTENSION AND RENAL FIBROSIS IN MICE​
  van Roeyen, C. R. C.; Drescher, A.; Hess, K.; Boor, P.; Martin, I. V.; Zok, S. & Braun, G. et al.​ (2014)
  Nephrology Dialysis Transplantation, 29 ​51st Congress of the European-Renal-Association(ERA)/European-Dialysis-and-Transplant-Associa tion (EDTA)​, Amsterdam, NETHERLANDS.
  Oxford​: Oxford Univ Press.
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• 2014 | Journal Article
  ​ ​Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice​
  Rubel, D.; Frese, J.; Martin, M.; Leibnitz, A.; Girgert, R.; Miosge, N. & Eckes, B. et al.​ (2014) 
  Matrix Biology, 34 pp. 13​-21​.​ DOI: https://doi.org/10.1016/j.matbio.2014.01.006 
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• 2014 | Journal Article | Letter Note
  ​ ​Challenges for Academic Investigator-Initiated Pediatric Trials for Rare Diseases​
  Ahmed, R.; Duerr, U.; Gavenis, K.; Hilgers, R.   & Gross, O.​ (2014) 
  Clinical Therapeutics, 36(2) pp. 184​-190​.​ DOI: https://doi.org/10.1016/j.clinthera.2014.01.013 
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• 2014 | Journal Article | 
  ​ ​Effects of mycophenolate mofetil on kidney function and phosphorylation status of renal proteins in Alport COL4A3-deficient mice​
  Petrova, D. T.; Schultze, F. C.; Brandhorst, G.; Luchs, K.-D.; Lenz, C.; Urlaub, H. & Rubel, D. et al.​ (2014) 
  Proteome Science, 12 art. 56​.​ DOI: https://doi.org/10.1186/s12953-014-0056-z 
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• 2014 | Journal Article | 
  ​ ​The 2014 International Workshop on Alport Syndrome.​
  Miner, J. H.; Baigent, C.; Flinter, F.; Gross, O.; Judge, P.; Kashtan, C. E. & Lagas, S. et al.​ (2014) 
  Kidney international, 86(4) pp. 679​-684​.​ DOI: https://doi.org/10.1038/ki.2014.229 
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• 2015 | Journal Article | 
  ​ ​Intensive Supportive Care plus Immunosuppression in IgA Nephropathy​
  Rauen, T.; Eitner, F.; Fitzner, C.; Sommerer, C.; Zeier, M.; Otte, B. & Panzer, U. et al.​ (2015) 
  New England Journal of Medicine, 373(23) pp. 2225​-2236​.​ DOI: https://doi.org/10.1056/NEJMoa1415463 
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• 2015 | Journal Article
  ​ ​Preclinical Alterations in the Serum of COL(IV)A3(-)/(-) Mice as Early Biomarkers of Alport Syndrome​
  Muckova, P.; Wendler, S.; Rubel, D.; Buechler, R.; Alert, M.; Gross, O. & Rhode, H.​ (2015) 
  Journal of Proteome Research, 14(12) pp. 5202​-5214​.​ DOI: https://doi.org/10.1021/acs.jproteome.5b00814 
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• 2016 | Conference Abstract
  ​ ​POTENTIAL OF RAAS-BLOCKADE TO DELAY RENAL DISEASE IN PATIENTS WITH ALPORT SYNDROME: A 4-YEAR PROSPECTIVE STUDY​
  Stock, J. ; Glonke, N.; Sonntag, J. ; Kuenanz, J. & Gross, O.​ (2016)
  Nephrology Dialysis Transplantation, 31 ​53rd ERA-EDTA Congress​, Vienna, AUSTRIA.
  Oxford​: Oxford Univ Press.
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• 2017 | Review
  ​ ​Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome​
  Gross, O.; Kashtan, C. E.; Rheault, M. N.; Flinter, F.; Savige, J.; Miner, J. H.& Torra, R. et al.​ (2017)
  Nephrology Dialysis Transplantation, 32​(6) pp. 916​-924​.​
  Oxford Univ Press. DOI: https://doi.org/10.1093/ndt/gfw095 
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• 2017 | Journal Article
  ​ ​Prospective study on the potential of RAAS blockade to halt renal disease in Alport syndrome patients with heterozygous mutations​
  Stock, J.; Kuenanz, J.; Glonke, N.; Sonntag, J.; Frese, J.; Toenshoff, B. & Hoecker, B. et al.​ (2017) 
  Pediatric Nephrology, 32(1) pp. 131​-137​.​ DOI: https://doi.org/10.1007/s00467-016-3452-z 
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• 2019 | Journal Article | 
  ​ ​Genetische Ursachen und Therapie beim Alport-Syndrom​
  Gross, O. & Hoefele, J.​ (2019) 
  Medizinische Genetik,(4) pp. 429​-437​.​ DOI: https://doi.org/10.1007/s11825-018-0214-2 
  ​Details  DOI 

• 2019 | Journal Article | Research Paper | 
  ​ ​Kidney Injury by Variants in the COL4A5 Gene Aggravated by Polymorphisms in Slit Diaphragm Genes Causes Focal Segmental Glomerulosclerosis.​
  Frese, J.; Kettwig, M.; Zappel, H.; Hofer, J.; Gröne, H.-J.; Nagel, M. & Sunder-Plassmann, G. et al.​ (2019) 
  International Journal of Molecular Sciences, 20(3) art. 519​.​ DOI: https://doi.org/10.3390/ijms20030519 
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