Author Loeffler, Markus

1 to 100 of 122 Items

2000 | Conference Abstract
Dose escalated BEACOPP chemotherapy improves failure free survival in advanced Hodgkin's disease: Updated results of the German Hodgkin's Lymphoma Study Group.
Diehl, V.; Franklin, J.; Sieber, M.; Hasenclever, D.; Wolf, J.; Engert, A. & Hermann, R. et al. (2000)
Blood, 96(11) pp. 576A-+.
Washington: Amer Soc Hematology.
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2002 | Conference Abstract
Significant dose escalation of the CHOEP regimen in young patients with aggressive non Hodgkin's lymphoma is feasible: Results of a prospective randomized phase I/II trial.
Truemper, L. H.; Kloss, M.; Held, G.; Schmits, R.; Franke, A.; Berdel, W. E. & Fischer, T. et al. (2002)
Blood, 100(11) 44th Annual Meeting of the American-Society-of-Hematology, PHILADELPHIA, PENNSYLVANIA.
Washington: Amer Soc Hematology.
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2002 | Conference Abstract
Mega-CHOEP repeated high dose therapy as treatment of aggressive NHL: Critical impact of time scheduling.
Glass, B.; Kloess, M.; Engert, A.; Berdel, W. E.; Metzner, B.; Truemper, L. H. & Loeffler, M. et al. (2002)
Blood, 100(11) 44th Annual Meeting of the American-Society-of-Hematology, PHILADELPHIA, PENNSYLVANIA.
Washington: Amer Soc Hematology.
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2003 | Conference Abstract
Repeated high-dose therapy with rituximab followed by autologous stem cell transplantation (ASCT) as primary treatment of high-risk aggressive NHL.
Glass, B.; Kloess, M.; Engert, A.; Berdel, W. E.; Metzner, B.; Truemper, L. H. & Loeffler, M. et al. (2003)
Blood, 102(11) 45th Annual Meeting of the American-Society-of-Hematology, SAN DIEGO, CALIFORNIA.
Washington: Amer Soc Hematology.
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2003 | Journal Article
Practicability and acute haematological toxicity of 2-and 3-weekly CHOP and CHOEP chemotherapy for aggressive non-Hodgkin's lymphoma: results from the NHL-B trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
Wunderlich, A.; Kloess, M.; Reiser, M.; Rudolph, C.; Truemper, L. H.; Bittner, S. & Schmalenberg, H. et al. (2003)
Annals of Oncology, 14(6) pp. 881-893. DOI: https://doi.org/10.1093/annonc/mdg249
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2004 | Conference Abstract
Early dose intensity is critical in patients with aggressive lymphoma: A randomized study comparing identical doses of cyclophosphamide, adriamycin, vincristine, etoposide, and prednisolone given as 4 or 6 cycles followed by repetitive transplantation of stem cells (Mega-CHOEP).
Glass, B.; Kloess, M.; Reiser, M.; Berdel, W. E.; Ho, A. D.; Truemper, L. H. & Loeffler, M. et al. (2004)
Blood, 104(11) 46th Annual Meeting of the American-Society-of-Hematology, San Diego, CA.
Washington: Amer Soc Hematology.
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2004 | Conference Abstract
First analysis of the completed Mabthera International (MInT) trial in young patients with low-risk diffuse large B-cell lymphoma (DLBCL): Addition of rituximab to a CHOP-like regimen significantly improves outcome of all patients with the identification of a very favorable subgroup with IPI=O and no bulky disease.
Pfreundschuh, M.; Truemper, L. H.; Gill, D. S.; Osterborg, A.; Pettengell, R.; Trneny, M. & Imrie, K. et al. (2004)
Blood, 104(11) 46th Annual Meeting of the American-Society-of-Hematology, San Diego, CA.
Washington: Amer Soc Hematology.
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2004 | Conference Abstract
Repetitive high-dose therapy with dose escalated CHOP plus Etoposide followed by autologous stem cell transplantation (Mega-CHOEP) in younger patients with primary diagnosis of aggressive NHL and elevated LDH at diagnosis: Final analysis
Schmitz, N.; Kloess, M.; Engert, A.; Berdel, W. E.; Metzner, B.; Truemper, L. H. & Loeffler, M. et al. (2004)
Blood, 104(11) 46th Annual Meeting of the American-Society-of-Hematology, San Diego, CA.
Washington: Amer Soc Hematology.
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2004 | Conference Abstract
Nad(p)h oxidase and MRP genetic polymorphisms associate with doxorubicin-induced cardiotoxicity
Wojnowski, L.; Schlueter, G.; Vonhof, S.; Kulle, B.; Bickeboeller, H. ; Loeffler, M. & Pfreundschuh, M. et al. (2004)
Journal of Clinical Oncology, 22(14) 40th Annual Meeting of the American-Society-of-Clinical-Oncology, New Orleans, LA.
Alexandria: Amer Soc Clinical Oncology.
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2004 | Conference Abstract
Association of NAD(P)H oxidase and MRP genetic polymorphisms with doxorubicin-induced cardiotoxicity
Wojnowski, L.; Schluter, G.; Vonhof, S.; Kulle, B.; Bickeboeller, H. ; Toliat, M. R. & Suk, E. K. et al. (2004)
Naunyn-Schmiedeberg s Archives of Pharmacology, 369 45th Spring Meeting of the German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology, Mainz, GERMANY.
New york: Springer.
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2004 | Conference Abstract
NAD(P)H oxidase and MRP genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity
Schirmer, M. A.; Wojnowski, L.; Schluter, G.; Vonhof, S.; Kulle, B.; Bickeboeller, H. & Toliat, M. R. et al. (2004)
Circulation, 110(17) pp. 807-808. 77th Scientific Meeting of the American-Heart-Association, New Orleans, LA.
Philadelphia: Lippincott Williams & Wilkins.
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2004 | Journal Article
Two-weekly or 3-weekly CHOP chemotherapy with or without etoposide for the treatment of young patients with good-prognosis (normal LDH) aggressive lymphomas: results of the NHL-B1 trial of the DSHNHL
Pfreundschuh, M.; Truemper, L. H.; Kloess, M.; Schmits, R.; Feller, A. C.; Rudolph, C. & Reiser, M. et al. (2004)
Blood, 104(3) pp. 626-633. DOI: https://doi.org/10.1182/blood-2003-06-2094
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2004 | Journal Article
Two-weekly or 3-weekly CHOP chemotherapy with or without etoposide for the treatment of elderly patients with aggressive lymphomas: results of the NHL-B2 trial of the DSHNHL
Pfreundschuh, M.; Truemper, L. H.; Kloess, M.; Schmits, R.; Feller, A. C.; Rube, C. & Rudolph, C. et al. (2004)
Blood, 104(3) pp. 634-641. DOI: https://doi.org/10.1182/blood-2003-06-2095
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2005 | Conference Abstract
Dose escalated CHOP plus etoposide followed by repetitive autologous stem cell transplantation (MegaCHOEP) with or without rituximab for primary treatment of aggressive NHL.
Glass, B.; Kloess, M.; Reiser, M.; Metzner, B.; Truemper, L. H.; Loeffler, M. & Pfreundschuh, M. et al. (2005)
Blood, 106(11) 47th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA.
Washington: Amer Soc Hematology.
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2005 | Conference Abstract
Dose escalated CHOP plus etoposide and repetitive autologous stem cell transplantation (MegaCHOEP) with and without rituximab for primary treatment of aggressive NHL.
Glass, B.; Kloess, M.; Engert, A.; Berdel, W. E.; Metzner, B.; Tromper, L. & Loeffler, M. et al. (2005)
Journal of Clinical Oncology, 23(16) 41st Annual Meeting of the American-Society-of-Clinical-Oncology, Orlando, FL.
Alexandria: Amer Soc Clinical Oncology.
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2005 | Conference Abstract
Interleukin-10 gene promoter polymorphisms in aggressive non-Hodgkin lymphoma
Kube, D.; Hua, T.; Kulle, B.; Gocht, D.; Kloess, M.; Brockmoeller, J. & Wojnowski, L. et al. (2005)
Annals of Oncology, 16 9th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2005 | Conference Abstract
Toxicity risk groups in aggressive NHL - Prognostic factors for hematotoxicity
Kloess, M.; Schmits, R.; Truemper, L. H.; Pfreundschuh, M. & Loeffler, M. (2005)
Annals of Oncology, 16 9th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2005 | Conference Abstract
Prognostic relevance of extrlymphatic involvement in aggressive lymphoma Results from a large randomized multicenter trial of the DSHNHL
Kempf, B.; Kloess, M.; Schmits, R.; Loeffler, M.; Truemper, L. H. & Pfreundschuh, M. (2005)
Annals of Oncology, 16 9th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2005 | Journal Article | Research Paper
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity
Wojnowski, L.; Kulle, B.; Schirmer, M. ; Schlüter, G.; Schmidt, A.; Rosenberger, A. & Vonhof, S. et al. (2005)
Circulation, 112(24) pp. 3754-3762. DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.576850
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2006 | Conference Abstract
Dose escalated CHOP plus etoposide with repetitive autologous stem cell transplantation as primary treatment for aggressive T-NHL: results of three consecutive phase I/II trials
Nickelsen, M.; Kloess, M.; Loeffler, M.; Glass, B.; Truemper, L. H.; Pfreundschuh, M. & Schmitz, N. (2006)
Bone Marrow Transplantation, 37 , Hamburg, GERMANY.
London: Nature Publishing Group.
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2006 | Conference Abstract
CHOP/CHOEP-14 followed by consolidation with alemtuzumab in untreated aggressive T-cell lymphomas (DSHNHL 2003-1): Feasibility and toxicity of a phase II trial of the German High Grade Non-Hodgkin's Lymphoma Group DSHNHL.
Truemper, L. H.; Hohloch, K.; Kloess, M.; Duehrsen, U.; Eimermacher, H.; Haas, A. & Aldaoud, A. et al. (2006)
Journal of Clinical Oncology, 24(18) 42nd Annual Meeting of the American-Society-of-Clinical-Oncology, Atlanta, GA.
Alexandria: Amer Soc Clinical Oncology.
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2006 | Journal Article
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling
Hummel, M.; Bentink, S.; Berger, H.; Klapper, W.; Wessendorf, S.; Barth, T. F. E. & Bernd, H. W. et al. (2006)
New England Journal of Medicine, 354(23) pp. 2419-2430. DOI: https://doi.org/10.1056/NEJMoa055351
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2006 | Journal Article
Four versus six courses of a dose-escalated cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regimen plus etoposide (MegaCHOEP) and autologous stem cell transplantation - Early dose intensity is crucial in treating younger patients with poor prognosis aggressive lymphoma
Schmitz, N.; Kloess, M.; Reiser, M.; Berdel, W. E.; Metzner, B.; Dorken, B. & Kneba, M. et al. (2006)
Cancer, 106(1) pp. 136-145. DOI: https://doi.org/10.1002/cncr.21588
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2006 | Journal Article
CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group
Pfreundschuh, M.; Truemper, L. H.; Osterborg, A.; Pettengell, R.; Trneny, M.; Imrie, K. & Ma, D. et al. (2006)
The Lancet Oncology, 7(5) pp. 379-391. DOI: https://doi.org/10.1016/S1470-2045(06)70664-7
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2007 | Conference Abstract
The ventilation strageties influence outcome in patients with severe sepsis - results from a national prospective multicenter study
Schaedler, D.; Schmitz, G.; Engel, C.; Bogatsch, H.; Frerichs, I.; Kuhlen, R. & Quintel, M. et al. (2007)
Infection, 35
Munich: Urban & Vogel.
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2007 | Conference Abstract
Final analysis of phase II study of CHOP/CHOEP-14 followed by consolidation with alemtuzumab in untreated aggressive T-cell lymphomas (DSHNHL 2003-1)
Binder, C.; Zielert, M.; Loeffler, M.; Pfreundschuli, M.; Schmitz, N.; Duehrsen, U. & Eimermacher, H. et al. (2007)
Blood, 110(11) pp. 1005A-1006A. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA.
Washington: Amer Soc Hematology.
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2007 | Journal Article
Prevalence and natural history of heart failure in outpatient HIV-infected subjects: Rationale and design of the HIV-heart study
Neumann, T.; Esser, S.; Potthoff, A.; Pankuweit, S.; Neumann, A.; Breuckmann, F. & Neuhaus, K. et al. (2007)
EUROPEAN JOURNAL OF MEDICAL RESEARCH, 12(6) pp. 243-248.
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2007 | Journal Article
The interleukin-10 gene promoter polymorphism - 1087AG does not correlate with clinical outcome in non-Hodgkin's lymphoma
Kube, D.; Hua, T.-D.; Kloess, M.; Kulle, B.; Brockmoeller, J.; Wojnowski, L. & Loeffler, M. et al. (2007)
Genes and Immunity, 8(2) pp. 164-167. DOI: https://doi.org/10.1038/sj.gene.6364364
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2007 | Journal Article
Epidemiology of sepsis in Germany: results from a national prospective multicenter study
Engel, C.; Brunkhorst, F. M.; Bone, H.-G.; Brunkhorst, R.; Gerlach, H.; Grond, S. & Gruendling, M. et al. (2007)
Intensive Care Medicine, 33(4) pp. 606-618. DOI: https://doi.org/10.1007/s00134-006-0517-7
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2008 | Conference Abstract
Response adapted assignment of the number of chemotherapy cycles for the treatment of patients with Diffuse Large B-cell Lymphoma (DLBCL) is not justified: Results of the RICOVER-60 trial of the German high-grade non-hodgkin lymphoma study group (DSHNHL)
Schubert, J.; Ziepert, M.; Lengfelder, E.; Mohren, M.; Peter, N.; Reiser, M. & Clemens, M. et al. (2008)
Onkologie, 31
Basel: Karger.
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2008 | Conference Abstract
Conserved oncogenic module activation patterns (COMAPS) identify biologically homogeneous groups of diffuse large B-cell lymphomas and clearly define Burkitt lymphoma
Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Conference Abstract
T-cell lymphomas in studies of the German high-grade NHL study group (DSHNHL)
Schmitz, N.; Ziepert, M.; Nickelsen, M.; Truemper, L. H.; Glass, B.; Loeffler, M. & Ho, A. D. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Conference Abstract
Different subtypes of aggressive B cell lymphomas share an epigenetic signature enriched for polycomb targets in stem cells
Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Klapper, W.; Wickham-Garcia, E. & Rosolowski, M. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Journal Article
Practice and perception - A nationwide survey of therapy habits in sepsis
Brunkhorst, F. M.; Engel, C.; Ragaller, M.; Welte, T.; Rossaint, R.; Gerlach, H. & Mayer, K. et al. (2008)
Critical Care Medicine, 36(10) pp. 2719-2725. DOI: https://doi.org/10.1097/CCM.0b013e318186b6f3
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2008 | Journal Article
Pathway activation patterns in diffuse large B-cell lymphomas
Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al. (2008)
Leukemia, 22(9) pp. 1746-1754. DOI: https://doi.org/10.1038/leu.2008.166
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2008 | Journal Article
Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials
Klapper, W.; Szczepanowski, M.; Burkhardt, B.; Berger, H.; Rosolowski, M.; Bentink, S. & Schwaenen, C. et al. (2008)
Blood, 112(4) pp. 1374-1381. DOI: https://doi.org/10.1182/blood-2008-01-136465
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2008 | Journal Article | Letter Note
Study protocol of the VISEP-Study. Answer of the SepNet-Study group
Reinhart, K.; Brunkhorst, F. M.; Engel, C.; Bloos, F.; Meier-Hellmann, A.; Ragaller, M. & Weiler, N. et al. (2008)
Der Anaesthesist, 57(7) pp. 723-728. DOI: https://doi.org/10.1007/s00101-008-1391-1
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2008 | Journal Article
Effect of interleukin-10 gene polymorphisms on clinical outcome of patients with aggressive non-Hodgkin's lymphoma: An exploratory study
Kube, D.; Hua, T.-D.; von Bonin, F.; Schoof, N.; Zeynalova, S.; Kloess, M. & Gocht, D. et al. (2008)
Clinical Cancer Research, 14(12) pp. 3777-3784. DOI: https://doi.org/10.1158/1078-0432.CCR-07-5182
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2008 | Journal Article
Prognostic factors for hematotoxicity of chemotherapy in aggressive non-Hodgkin's lymphoma
Ziepert, M.; Schmits, R.; Truemper, L. H.; Pfreundschuh, M. & Loeffler, M. (2008)
Annals of Oncology, 19(4) pp. 752-762. DOI: https://doi.org/10.1093/annonc/mdm541
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2008 | Journal Article |
Intensive insulin therapy and pentastarch resuscitation in severe sepsis
Brunkhorst, F. M.; Engel, C.; Bloos, F.; Meier-Hellmann, A.; Ragaller, M.; Weiler, N. & Moerer, O. et al. (2008)
New England Journal of Medicine, 358(2) pp. 125-139. DOI: https://doi.org/10.1056/NEJMoa070716
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2008 | Journal Article
Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60)
Pfreundschuh, M.; Schubert, J.; Ziepert, M.; Schmits, R.; Mohren, M.; Lengfelder, E. & Reiser, M. et al. (2008)
The Lancet Oncology, 9(2) pp. 105-116. DOI: https://doi.org/10.1016/S1470-2045(08)70002-0
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2008 | Journal Article
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma
Dierlamm, J.; Penas, E. M. M.; Bentink, S.; Wessendorf, S.; Berger, H.; Hummel, M. & Klapper, W. et al. (2008)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 93(5) pp. 688-696. DOI: https://doi.org/10.3324/haematol.12057
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2008 | Journal Article
Dose-escalated CHOEP for the treatment of young patients with aggressive non-Hodgkin's lymphoma: II. Results of the randomized high-CHOEP trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
Pfreundschuh, M.; Zwick, C.; Zeynalova, S.; Duehrsen, U.; Ger, K. Ger, K.-H. Pflu; Vrieling, T. & Mesters, R. et al. (2008)
Annals of Oncology, 19(3) pp. 545-552. DOI: https://doi.org/10.1093/annonc/mdm514
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2008 | Journal Article
Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
Klapper, W.; Stoecklein, H.; Zeynalova, S.; Ott, G.; Kosari, F.; Rosenwald, A. & Loeffler, M. et al. (2008)
Leukemia, 22(12) pp. 2226-2229. DOI: https://doi.org/10.1038/leu.2008.230
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2009 | Conference Abstract
Mature T-/NK-cell lymphomas: Prognostic factors and treatment outcome of patients treated on studies of the German High-Grade Lymphoma Study Group (DSHNHL)
Schmitz, N.; Ziepert, M.; Nickelsen, M.; Wolf, S. P.; Truemper, L. H.; Loeffler, M. & Ho, A. D. et al. (2009)
Journal of Clinical Oncology, 27(15) 45th Annual Meeting of the American-Society-of-Clinical-Oncology, Orlando, FL.
Alexandria: Amer Soc Clinical Oncology.
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2009 | Conference Abstract
Aggressive Chemotherapy (CHOEP-14) and Rituximab or High-Dose Therapy (MegaCHOEP) and Rituximab for Young, High-Risk Patients with Aggressive B-Cell Lymphoma: Results of the MegaCHOEP Trial of the German High - Grade Non-Hodgkin Lymphoma Study Group (DSHNHL)
Schmitz, N.; Nickelsen, M.; Ziepert, M.; Haenel, M.; Borchmann, P.; Viardot, A. & Nickenig, C. et al. (2009)
Blood, 114(22) 51st Annual Meeting of the American-Society-of-Hematology, New Orleans, LA.
Washington: Amer Soc Hematology.
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2009 | Conference Abstract
Outcome of Elderly Patients with DLBCL Failing R-CHOP: The Role of Rituximab and High Dose Therapy in Second Line Treatment. A Retrospective Analysis From the RICOVER 60 Trial.
Glass, B.; Borgerding, A.; Ziepert, M.; Nickelsen, M.; Loeffler, M.; Pfreundschuh, M. & Truemper, L. H. et al. (2009)
Blood, 114(22) pp. 1430-1431. 51st Annual Meeting of the American-Society-of-Hematology, New Orleans, LA.
Washington: Amer Soc Hematology.
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2009 | Journal Article |
Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
Bernd, H.-W.; Ziepert, M.; Thorns, C.; Klapper, W.; Wacker, H.-H.; Hummel, M. & Stein, H. et al. (2009)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 94(11) pp. 1569-1580. DOI: https://doi.org/10.3324/haematol.2009.008862
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2009 | Journal Article |
Favorable impact of the interleukin-4 receptor allelic variant I75 on the survival of diffuse large B-cell lymphoma patients demonstrated in a large prospective clinical trial
Schoof, N.; von Bonin, F.; Zeynalova, S.; Ziepert, M.; Jung, W.; Loeffler, M. & Pfreundschuh, M. et al. (2009)
Annals of Oncology, 20(9) pp. 1548-1554. DOI: https://doi.org/10.1093/annonc/mdp110
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2009 | Journal Article
Microarray-Based Genomic Profiling Reveals Novel Genomic Aberrations in Follicular War Lymphoma Which Associate with Patient Survival and Gene Expression Status
Schwaenen, C.; Viardot, A.; Berger, H.; Barth, T. F. E.; Bentink, S.; Doehner, H. & Enz, M. et al. (2009)
Genes Chromosomes and Cancer, 48(1) pp. 39-54. DOI: https://doi.org/10.1002/gcc.20617
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2009 | Journal Article
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling
Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Ammerpohl, O.; Wickham-Garcia, E. & Rosolowski, M. et al. (2009)
Blood, 113(11) pp. 2488-2497. DOI: https://doi.org/10.1182/blood-2008-04-152900
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2009 | Journal Article
Escalated-Dose BEACOPP in the Treatment of Patients With Advanced-Stage Hodgkin's Lymphoma: 10 Years of Follow-Up of the GHSG HD9 Study
Engert, A.; Diehl, V.; Franklin, J.; Lohri, A.; Doerken, B.; Ludwig, W.-D. & Koch, P. et al. (2009)
Journal of Clinical Oncology, 27(27) pp. 4548-4554. DOI: https://doi.org/10.1200/JCO.2008.19.8820
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2010 | Conference Abstract
CNS Disease In Younger Patients (<=60 years) with Aggressive Lymphoma Treated In Trials of the German High Grade Non Hodgkin Lymphoma Study Group (DSHNHL) and the MabThera International Trial (MInT)
Schmitz, N.; Zeynalova, S.; Glass, B.; Kaiser, U.; Cavallin-Stahl, E.; Wolf, M. & Haenel, M. et al. (2010)
Blood, 116(21) 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando, FL.
Washington: Amer Soc Hematology.
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2010 | Conference Abstract
Randomised Intergroup Trial of First line Treatment for young Low-Risk Patients (< 61 years) with Diffuse Large B-Cell Non-Hodgkin's Lymphoma (DLBCL) with a CHOP-like Regimen with or without the Anti-CD20 Antibody Rituximab-6-Year Follow-up of the Mint Study of the Mabthera International Trial (MInT) Group
Pfreundschuh, M.; Kuhnt, E.; Truemper, L. H.; Osterborg, A.; Trneny, M.; Shepherd, L. & Gill, D. S. et al. (2010)
Blood, 116(21) 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando, FL.
Washington: Amer Soc Hematology.
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2010 | Journal Article
Treatment and prognosis of mature T-cell and NK-cell lymphoma: an analysis of patients with T-cell lymphoma treated in studies of the German High-Grade Non-Hodgkin Lymphoma Study Group
Schmitz, N.; Truemper, L. H.; Ziepert, M.; Nickelsen, M.; Ho, A. D.; Metzner, B. & Peter, N. et al. (2010)
Blood, 116(18) pp. 3418-3425. DOI: https://doi.org/10.1182/blood-2010-02-270785
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2010 | Journal Article
High-dose therapy followed by autologous stem-cell transplantation with and without rituximab for primary treatment of high-risk diffuse large B-cell lymphoma
Glass, B.; Ziepert, M.; Reiser, M.; Freund, M.; Trümper, L. ; Metzner, B. & Feller, A. et al. (2010)
Annals of Oncology, 21(11) pp. 2255-2261. DOI: https://doi.org/10.1093/annonc/mdq235
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2010 | Journal Article
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
Ott, G.; Ziepert, M.; Klapper, W.; Horn, H.; Szczepanowski, M.; Bernd, H.-W. & Thorns, C. et al. (2010)
Blood, 116(23) pp. 4916-4925. DOI: https://doi.org/10.1182/blood-2010-03-276766
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2010 | Journal Article | Letter Note
A network against failing hearts-Introducing the German "Competence Network Heart Failure"
Mehrhof, F.; Loeffler, M.; Gelbrich, G.; Oezcelik, C.; Posch, M. G.; Hense, H.-W. & Keil, U. et al. (2010)
International Journal of Cardiology, 145(1) pp. 135-138. DOI: https://doi.org/10.1016/j.ijcard.2009.06.061
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2010 | Journal Article |
Phosphoglycerate Kinase 1 Promoting Tumor Progression and Metastasis in Gastric Cancer - Detected in a Tumor Mouse Model Using Positron Emission Tomography/Magnetic Resonance Imaging
Zieker, D.; Koenigsrainer, I.; Weinreich, J.; Beckert, S.; Glatzle, J.; Nieselt, K. & Buehler, S. et al. (2010)
Cellular Physiology and Biochemistry, 26(2) pp. 147-154. DOI: https://doi.org/10.1159/000320545
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2010 | Journal Article
A Functional Polymorphism in the NAD(P)H Oxidase Subunit CYBA Is Related to Gene Expression, Enzyme Activity, and Outcome in Non-Hodgkin Lymphoma
Hoffmann, M.; Schirmer, M. A.; Tzvetkov, M. V.; Kreuz, M.; Ziepert, M.; Wojnowski, L. & Kube, D. et al. (2010)
Cancer Research, 70(6) pp. 2328-2338. DOI: https://doi.org/10.1158/0008-5472.CAN-09-2388
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2010 | Journal Article |
Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis
Scholtysik, R.; Kreuz, M.; Klapper, W.; Burkhardt, B.; Feller, A. C.; Hummel, M. & Loeffler, M. et al. (2010)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(12) pp. 2047-2055. DOI: https://doi.org/10.3324/haematol.2010.026831
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2010 | Journal Article
Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer
Zieker, D.; Koenigsrainer, I.; Tritschler, I.; Loeffler, M.; Beckert, S.; Traub, F. & Nieselt, K. et al. (2010)
International Journal of Cancer, 126(6) pp. 1513-1520. DOI: https://doi.org/10.1002/ijc.24835
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2011 | Conference Abstract
7-year follow-up of the RICOVER-60 trial of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL)
Zwick, C.; Ziepert, M.; Zeynalova, S.; Lengfelder, E.; Steinhauer, H.; Clemens, M. & Nickenig, C. et al. (2011)
Onkologie, 34
Basel: Karger.
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2011 | Conference Abstract
6-year follow-up of the mint study suggests a role for radiotherapy to bulky disease
Held, G.; Kuhnt, E.; Truemper, L. H.; Osterborg, A.; Trneny, M.; Shepherd, L. & Gill, D. S. et al. (2011)
Onkologie, 34
Basel: Karger.
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2011 | Conference Abstract
First Interim Safety Analysis of a Phase III Randomized Trial in Newly Diagnosed Systemic Peripheral T-Cell Lymphoma Treated with CHOP Chemotherapy with or without Alemtuzumab and Consolidated by Autologous Hematopoietic Stem Cell Transplant
d'Amore, F.; da Silva, M. G.; Leppa, S.; Relander, T.; Pezzutto, A.; Lauritzsen, G. F. & Weidmann, E. et al. (2011)
Blood, 118(21) 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA.
Washington: Amer Soc Hematology.
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2011 | Conference Abstract
EXCELLENT OUTCOME IN AGGRESSIVE NON HODGKIN'S LYMPHOMA IN ADOLESCENTS AND YOUNG ADULTS TREATED WITH CHOP-BASED REGIMENS IN DSHNHL TRIALS: AGE IS NOT A RISK FACTOR IN PATIENTS BELOW 50 YEARS
Truemper, L. H.; Zeynalova, S.; Ziepert, M.; Glass, B.; Loeffler, M.; Schmitz, N. & Pfreundschuh, M. (2011)
Annals of Oncology, 22 11th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2011 | Conference Abstract
CONVENTIONAL CHEMOIMMUNOTHERAPY (R-CHOEP-14) OR HIGH-DOSE THERAPY (R-MEGA-CHOEP) FOR YOUNG, HIGH-RISK PATIENTS WITH AGGRESSIVE B-CELL LYMPHOMA: FINAL RESULTS OF THE RANDOMIZED MEGA-CHOEP-TRIAL OF THE GERMAN HIGH-GRADE NON-HODGKIN LYMPHOMA STUDY GROUP (DSHNHL)
Schmitz, N.; Nickelsen, M.; Ziepert, M.; Borchmann, P.; Nickenig, C.; Viardot, A. & Bentz, M. et al. (2011)
Annals of Oncology, 22 pp. 106-107. 11th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2011 | Journal Article
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults
Salaverria, I.; Philipp, C.; Oschlies, I.; Kohler, C. W.; Kreuz, M.; Szczepanowski, M. & Burkhardt, B. et al. (2011)
Blood, 118(1) pp. 139-147. DOI: https://doi.org/10.1182/blood-2011-01-330795
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2011 | Journal Article | Research Paper
Exercise Training Improves Exercise Capacity and Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction Results of the Ex-DHF (Exercise training in Diastolic Heart Failure) Pilot Study
Edelmann, F. ; Gelbrich, G.; Duengen, H.-D.; Froehling, S.; Wachter, R. ; Stahrenberg, R. & Binder, L. et al. (2011)
Journal of the American College of Cardiology, 58(17) pp. 1780-1791. DOI: https://doi.org/10.1016/j.jacc.2011.06.054
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2011 | Journal Article
Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure
Waldmueller, S.; Erdmann, J.; Binner, P.; Gelbrich, G.; Pankuweit, S.; Geier, C. & Timmermann, B. et al. (2011)
European Journal of Heart Failure, 13(11) pp. 1185-1192. DOI: https://doi.org/10.1093/eurjhf/hfr074
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2011 | Journal Article
CHOP-like chemotherapy with or without rituximab in young patients with good-prognosis diffuse large-B-cell lymphoma: 6-year results of an open-label randomised study of the MabThera International Trial (MInT) Group
Pfreundschuh, M.; Kuhnt, E.; Truemper, L. H.; Osterborg, A.; Trneny, M.; Shepherd, L. & Gill, D. S. et al. (2011)
The Lancet Oncology, 12(11) pp. 1013-1022. DOI: https://doi.org/10.1016/S1470-2045(11)70235-2
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2012 | Conference Abstract
First Interim Efficacy and Safety Analysis of an International Phase III Randomized Trial in Newly Diagnosed Systemic Peripheral T-Cell Lymphoma Treated with Chemotherapy with or without Alemtuzumab and Consolidated by High Dose Therapy
d'Amore, F.; Leppa, S.; da Silva, M. C.; Relander, T.; Brown, P. D. N.; Weidmann, E. & Lauritzsen, G. F. et al. (2012)
Blood, 120(21) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta, GA.
Washington: Amer Soc Hematology.
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2012 | Conference Abstract
Sequencing of pediatric Burkitt lymphoma within the ICGC MMML-Seq project
Richter, J.; Schlesner, M.; Leich, E.; Burkhardt, B.; Hoffmann, S.; Szczepanowski, M. & Kreuz, M. et al. (2012)
British Journal of Haematology, 159 4th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkins Lymphoma, New York, NY.
Hoboken: Wiley-blackwell.
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2012 | Conference Abstract
SOCS1 Mutation Subtypes Predict Divergent Outcomes in DLBCL Patients
Lennerz, J. K.; Schif, B.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Truemper, L. H. et al. (2012)
Blood, 120(21) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta, GA.
Washington: Amer Soc Hematology.
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2012 | Journal Article
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
Richter, J.; Schlesner, M.; Hoffmann, S.; Kreuz, M.; Leich, E.; Burkhardt, B. & Rosolowski, M. et al. (2012)
Nature Genetics, 44(12) pp. 1316-1320. DOI: https://doi.org/10.1038/ng.2469
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2012 | Journal Article
Is target dose the treatment target? Uptitrating beta-blockers for heart failure in the elderly
Gelbrich, G.; Edelmann, F. T.; Inkrot, S.; Lainscak, M.; Apostolovic, S.; Neskovic, A. N. & Waagstein, F. et al. (2012)
International Journal of Cardiology, 155(1) pp. 160-166. DOI: https://doi.org/10.1016/j.ijcard.2011.11.018
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2012 | Journal Article
Conventional chemotherapy (CHOEP-14) with rituximab or high-dose chemotherapy (MegaCHOEP) with rituximab for young, high-risk patients with aggressive B-cell lymphoma: an open-label, randomised, phase 3 trial (DSHNHL 2002-1)
Schmitz, N.; Nickelsen, M.; Ziepert, M.; Haenel, M.; Borchmann, P.; Schmidt, C. D. & Viardot, A. et al. (2012)
The Lancet Oncology, 13(12) pp. 1250-1259. DOI: https://doi.org/10.1016/S1470-2045(12)70481-3
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2012 | Journal Article
Circulating Levels of TNF Receptor II Are Prognostic for Patients with Peripheral T-cell Non-Hodgkin Lymphoma
Heemann, C.; Kreuz, M.; Stoller, I.; Schoof, N.; von Bonin, F.; Ziepert, M. & Loeffler, M. et al. (2012)
Clinical Cancer Research, 18(13) pp. 3637-3647. DOI: https://doi.org/10.1158/1078-0432.CCR-11-3299
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2012 | Journal Article
Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis A Randomized Trial
Brunkhorst, F. M.; Oppert, M.; Marx, G.; Bloos, F.; Ludewig, K.; Putensen, C. & Nierhaus, A. et al. (2012)
JAMA, 307(22) pp. 2390-2399. DOI: https://doi.org/10.1001/jama.2012.5833
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2012 | Journal Article
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
Klapper, W.; Kreuz, M.; Kohler, C. W.; Burkhardt, B.; Szczepanowski, M.; Salaverria, I. & Hummel, M. et al. (2012)
Blood, 119(8) pp. 1882-1887. DOI: https://doi.org/10.1182/blood-2011-10-388470
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2012 | Journal Article
Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas
Scholtysik, R.; Nagel, I.; Kreuz, M.; Vater, I.; Giefing, M.; Schwaenen, C. & Wessendorf, S. et al. (2012)
International Journal of Cancer, 131(5) pp. E830-E835. DOI: https://doi.org/10.1002/ijc.27416
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2012 | Journal Article
CNS disease in younger patients with aggressive B-cell lymphoma: an analysis of patients treated on the Mabthera International Trial and trials of the German High-Grade Non-Hodgkin Lymphoma Study Group
Schmitz, N.; Zeynalova, S.; Glass, B.; Kaiser, U.; Cavallin-Stahl, E.; Wolf, M. & Haenel, M. et al. (2012)
Annals of Oncology, 23(5) pp. 1267-1273. DOI: https://doi.org/10.1093/annonc/mdr440
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2013 | Journal Article |
SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients.
Schif, B.; Lennerz, J. K.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Ritz, O. et al. (2013)
Oncotarget, 4(1) pp. 35-47.
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2013 | Journal Article | Research Paper
Effect of Spironolactone on Diastolic Function and Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction The Aldo-DHF Randomized Controlled Trial
Edelmann, F. ; Wachter, R. ; Schmidt, A. G.; Kraigher-Krainer, E.; Colantonio, C.; Kamke, W. & Duvinage, A. et al. (2013)
JAMA, 309(8) pp. 781-791. DOI: https://doi.org/10.1001/jama.2013.905
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2013 | Journal Article
CHO(E)P-14 followed by alemtuzumab consolidation in untreated peripheral T cell lymphomas: final analysis of a prospective phase II trial
Binder, C.; Ziepert, M.; Pfreundschuh, M.; Duehrsen, U.; Eimermacher, H.; Aldaoud, A. & Rosenwald, A. et al. (2013)
Annals of Hematology, 92(11) pp. 1521-1528. DOI: https://doi.org/10.1007/s00277-013-1880-4
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2013 | Journal Article
Ventilatory strategies in septic patients Results from a nationwide observational trial
Schaedler, D.; Elke, G.; Engel, C.; Bogatsch, H.; Frerichs, I.; Kuhlen, R. & Rossaint, R. et al. (2013)
Der Anaesthesist, 62(1) pp. 27-33. DOI: https://doi.org/10.1007/s00101-012-2121-2
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2013 | Journal Article
MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma
Horn, H.; Ziepert, M.; Becher, C.; Barth, T. F. E.; Bernd, H.-W.; Feller, A. C. & Klapper, W. et al. (2013)
Blood, 121(12) pp. 2253-2263. DOI: https://doi.org/10.1182/blood-2012-06-435842
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2014 | Conference Abstract
Increased rituximab (R) doses eliminate increased risk and improve outcome of elderly male patients with aggressive CD20+B-cell lymphomas: The SEXIE-R-CHOP-14 trial of the DSHNHL
Held, G.; Murawski, N.; Zeynalova, S.; Zwick, C.; Haenel, M.; Truemper, L. H. & Dreyling, M. et al. (2014)
Oncology Research and Treatment, 37
Basel: Karger.
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2014 | Conference Abstract
COMPARISON OF CONVENTIONAL CYTOGENETIC ANALYSIS AND WHOLE GENOME SEQUENCING IN GERMINAL-CENTER DERIVED B-CELL LYMPHOMAS IN THE FRAMEWORK OF THE ICGC MMML-SEQ PROJECT
Lopez, C.; Sungalee, S.; Bernhardt, S. H. S. H.; Schlesner, M.; Murga Penas, E. M.; Haake, A. & Richter, J. et al. (2014)
Haematologica, 99 pp. 407-408. 19th Congress of the European-Hematology-Association, Milan, ITALY.
Pavia: Ferrata Storti Foundation.
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2014 | Journal Article |
Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma
Aukema, S. M.; Kreuz, M.; Kohler, C. W.; Rosolowski, M.; Hasenclever, D.; Hummel, M. & Kueppers, R. et al. (2014)
Haematologica, 99(4) pp. 726-735. DOI: https://doi.org/10.3324/haematol.2013.091827
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2014 | Journal Article | Letter Note
Excellent outcome of young adults with aggressive non-Hodgkin lymphomas treated with CHOP-like regimens
Hohloch, K.; Zeynalova, S.; Held, G.; Ziepert, M.; Loeffler, M.; Wulf, G. & Schmitz, N. et al. (2014)
Leukemia, 28(11) pp. 2260-2263. DOI: https://doi.org/10.1038/leu.2014.213
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2014 | Journal Article |
Significant dose Escalation of Idarubicin in the treatment of aggressive Non- Hodgkin Lymphoma leads to increased hematotoxicity without improvement in efficacy in comparison to standard CHOEP-14: 9-year follow up results of the CIVEP trial of the DSHNHL
Hohloch, K.; Zwick, C.; Ziepert, M.; Hasenclever, D.; Kaiser, U.; Engert, A. & Hoeffkes, H.-G. et al. (2014)
SpringerPlus, 3 art. 5. DOI: https://doi.org/10.1186/2193-1801-3-5
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2014 | Journal Article
A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma
Salaverria, I.; Martin-Guerrero, I.; Wagener, R.; Kreuz, M.; Kohler, C. W.; Richter, J. & Pienkowska-Grela, B. et al. (2014)
Blood, 123(8) pp. 1187-1198. DOI: https://doi.org/10.1182/blood-2013-06-507996
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2015 | Conference Abstract
ANALYSIS OF MECHANISMS OF MALIGNANT TRANSFORMATION IN TP53 WILD-TYPE BURKITT'S LYMPHOMA BY INTEGRATION OF MOLECULAR AND FUNCTIONAL GENOMICS DATA
Huellein, J.; Slabicki, M.; Rosolowski, M.; Scholtysik, R.; Jethwa, A.; Lukas, M. & Tomska, K. et al. (2015)
Haematologica, 100 20th Congress of European-Hematology-Association, Vienna, AUSTRIA.
Pavia: Ferrata Storti Foundation.
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2015 | Conference Abstract
Obesity Is a Prognostic Factor in Elderly Female Patients with Aggressive B-Cell Lymphomas Treated with R-CHOP
Hohloch, K.; Altmann, B.; Pfreundschuh, M.; Loeffler, M.; Schmitz, N.; Ziepert, M. & Truemper, L. H. (2015)
Blood, 126(23) 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL.
Washington: Amer Soc Hematology.
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2015 | Conference Abstract
Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma
Chapuy, B. ; Dunford, A. J.; Stewart, C.; Kamburov, A.; Kim, J.; Roemer, M. G. M. & Ziepert, M. et al. (2015)
Blood, 126(23) 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL.
Washington: Amer Soc Hematology.
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2015 | Journal Article
Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis
Scholtysik, R.; Kreuz, M.; Hummel, M.; Rosolowski, M.; Szczepanowski, M.; Klapper, W. & Loeffler, M. et al. (2015)
International Journal of Cancer, 136(5) pp. 1033-1042. DOI: https://doi.org/10.1002/ijc.29072
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2015 | Journal Article
MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells
Doose, G.; Haake, A.; Bernhart, S. H.; Lopez, C.; Duggimpudi, S.; Wojciech, F. & Bergmann, A. K. et al. (2015)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(38) pp. E5261-E5270. DOI: https://doi.org/10.1073/pnas.1505753112
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2015 | Journal Article
The PCBP1 gene encoding poly(rc) binding protein i is recurrently mutated in Burkitt lymphoma
Wagener, R.; Aukema, S. M.; Schlesner, M.; Haake, A.; Burkhardt, B.; Claviez, A. & Drexler, H. G. et al. (2015)
Genes Chromosomes and Cancer, 54(9) pp. 555-564. DOI: https://doi.org/10.1002/gcc.22268
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2015 | Journal Article
Suffering as an independent component of the experience ofpain
Bustan, S.; Gonzalez-Roldan, A. M.; Kamping, S.; Brunner, M.; Loeffler, M.; Flor, H. & Anton, F. (2015)
European Journal of Pain, 19(7) pp. 1035-1048. DOI: https://doi.org/10.1002/ejp.709
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