Author Kehlenbach, Ralph H.

• 2006 | Conference Abstract
  ​ ​Nup214 is required for efficient nuclear protein export in vivo​
  Hutten, S. & Kehlenbach, R. H.​ (2006)
  European Journal of Cell Biology, 85 ​29th Annual Meeting of the German Society for Cell Biology​, Braunschweig, GERMANY.
  Jena​: Elsevier Gmbh, Urban & Fischer Verlag.
  ​Details  WoS 

• 2006 | Journal Article
  ​ ​Nup214 is required for CRM1-dependent nuclear protein export in vivo​
  Hutten, S. & Kehlenbach, R. H.​ (2006) 
  Molecular and Cellular Biology, 26(18) pp. 6772​-6785​.​ DOI: https://doi.org/10.1128/MCB.00342-06 
  ​Details  DOI  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1​
  Arnold, M.; Nath, A.; Hauber, J. & Kehlenbach, R. H.​ (2006) 
  Journal of Biological Chemistry, 281(30) pp. 20883​-20890​.​ DOI: https://doi.org/10.1074/jbc.M602189200 
  ​Details  DOI  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Transportin is a major nuclear import receptor for c-Fos - A novel mode of cargo interaction​
  Arnold, M.; Nath, A.; Wohlwend, D. & Kehlenbach, R. H.​ (2006) 
  Journal of Biological Chemistry, 281(9) pp. 5492​-5499​.​ DOI: https://doi.org/10.1074/jbc.M513281200 
  ​Details  DOI  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element​
  Prechtel, A. T.; Chemnitz, J.; Schirmer, S.; Ehlers, C.; Langbein-Detsch, I.; Stulke, J. & Dabauvalle, M. C. et al.​ (2006) 
  Journal of Biological Chemistry, 281(16) pp. 10912​-10925​.​ DOI: https://doi.org/10.1074/jbc.M510306200 
  ​Details  DOI  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Stimulated expression of mRNAs in activated T cells depends on a functional CRM1 nuclear export pathway​
  Schutz, S.; Chemnitz, J.; Spillner, C.; Frohme, M.; Hauber, J. & Kehlenbach, R. H.​ (2006) 
  Journal of Molecular Biology, 358(4) pp. 997​-1009​.​ DOI: https://doi.org/10.1016/j.jmb.2006.02.041 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Journal Article
  ​ ​Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expression​
  Fries, B.; Heukeshoven, J.; Hauber, I.; Gruettner, C.; Stocking, C.; Kehlenbach, R. H. & Hall, J. et al.​ (2007) 
  Journal of Biological Chemistry, 282(7) pp. 4504​-4515​.​ DOI: https://doi.org/10.1074/jbc.M608849200 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Journal Article
  ​ ​Nuclear import of c-Jun is mediated by multiple transport receptors​
  Waldmann, I.; Waelde, S. & Kehlenbach, R. H.​ (2007) 
  Journal of Biological Chemistry, 282(38) pp. 27685​-27692​.​ DOI: https://doi.org/10.1074/jbc.M703301200 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Review
  ​ ​CRM1-mediated nuclear export: to the pore and beyond​
  Hutten, S.& Kehlenbach, R. H.​ (2007)
  Trends in Cell Biology, 17​(4) pp. 193​-201​.​
  Elsevier Science London. DOI: https://doi.org/10.1016/j.tcb.2007.02.003 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Conference Abstract
  ​ ​Nup358-RanGAP is required for efficient importin alpha/beta dependent nuclear import​
  Kehlenbach, R. H.; Flotho, A.; Melchior, F. & Hutten, S.​ (2008)
  European Journal of Cell Biology, 87 ​31st Annual Meeting of the German-Society-for-Cell-Biology​, Marburg, GERMANY.
  Jena​: Elsevier Gmbh, Urban & Fischer Verlag.
  ​Details  WoS 

• 2008 | Journal Article | 
  ​ ​The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import​
  Hutten, S.; Flotho, A.; Melchior, F. & Kehlenbach, R. H.​ (2008) 
  Molecular Biology of the Cell, 19(5) pp. 2300​-2310​.​ DOI: https://doi.org/10.1091/mbc.E07-12-1279 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Conference Abstract
  ​ ​Subcellular localization as a modulator of polyQ disease severity​
  Schmidt, T.; Antony, P. M. A.; Maentele, S.; Mollenkopf, P.; Boy, J.; Kehlenbach, R. H. & Riess, O.​ (2009)
  Journal of Neurochemistry, 110 , Leipzig, GERMANY.
  Malden​: Wiley-blackwell Publishing, Inc.
  ​Details  WoS 

• 2009 | Journal Article
  ​ ​Identification and functional dissection of localization signals within ataxin-3​
  Antony, P. M. A.; Maentele, S.; Mollenkopf, P.; Boy, J.; Kehlenbach, R. H.; Riess, O. & Schmidt, T.​ (2009) 
  Neurobiology of Disease, 36(2) pp. 280​-292​.​ DOI: https://doi.org/10.1016/j.nbd.2009.07.020 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article | 
  ​ ​The nuclear pore component Nup358 promotes transportin-dependent nuclear import​
  Hutten, S.; Waelde, S.; Spillner, C.; Hauber, J. & Kehlenbach, R. H.​ (2009) 
  Journal of Cell Science, 122(8) pp. 1100​-1110​.​ DOI: https://doi.org/10.1242/jcs.040154 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Conference Abstract
  ​ ​The cytoplasmic nucleoporin Nup358 promotes nuclear accumulation of a subset of cellular proteins​
  Waelde, S. & Kehlenbach, R. H.​ (2010)
  European Journal of Cell Biology, 89 pp. 46​-47. ​33rd Annual Meeting of the German-Society-for-Cell-Biology/German Melanoma Research Network​, Univ Regensburg, Regensburg, GERMANY.
  Jena​: Elsevier Gmbh, Urban & Fischer Verlag.
  ​Details  WoS 

• 2010 | Journal Article
  ​ ​The Anti-inflammatory Prostaglandin 15-Deoxy-Delta(12,14)-PGJ(2) Inhibits CRM1-dependent Nuclear Protein Export​
  Hilliard, M.; Frohnert, C.; Spillner, C.; Marcone, S.; Nath, A.; Lampe, T. & Fitzgerald, D. J. et al.​ (2010) 
  Journal of Biological Chemistry, 285(29) pp. 22202​-22210​.​ DOI: https://doi.org/10.1074/jbc.M110.131821 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Review
  ​ ​The Part and the Whole: functions of nucleoporins in nucleocytoplasmic transport​
  Waelde, S.& Kehlenbach, R. H.​ (2010)
  Trends in Cell Biology, 20​(8) pp. 461​-469​.​
  Elsevier Science London. DOI: https://doi.org/10.1016/j.tcb.2010.05.001 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Journal Article | 
  ​ ​Notch1 signaling is mediated by importins alpha 3, 4, and 7​
  Huenniger, K.; Kraemer, A.; Soom, M.; Chang, I.; Koehler, M.; Depping, R. & Kehlenbach, R. H. et al.​ (2010) 
  Cellular and Molecular Life Sciences, 67(18) pp. 3187​-3196​.​ DOI: https://doi.org/10.1007/s00018-010-0378-7 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Journal Article | 
  ​ ​Functional Characterization of the HuR:CD83 mRNA Interaction​
  Pieper, D.; Schirmer, S.; Prechtel, A. T.; Kehlenbach, R. H.; Hauber, J. & Chemnitz, J.​ (2011) 
  PLoS ONE, 6(8) art. e23290​.​ DOI: https://doi.org/10.1371/journal.pone.0023290 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Journal Article | 
  ​ ​Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability​
  Hamada, M.; Haeger, A.; Jeganathan, K. B.; van Ree, J. H.; Malureanu, L.; Waelde, S. & Joseph, J. et al.​ (2011) 
  The Journal of Cell Biology, 194(4) pp. 597​-612​.​ DOI: https://doi.org/10.1083/jcb.201102018 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Journal Article
  ​ ​The Nucleoporin Nup358/RanBP2 Promotes Nuclear Import in a Cargo- and Transport Receptor-Specific Manner​
  Waelde, S.; Thakar, K.; Hutten, S.; Spillner, C.; Nath, A.; Rothbauer, U. & Wiemann, S. et al.​ (2012) 
  Traffic, 13(2) pp. 218​-233​.​ DOI: https://doi.org/10.1111/j.1600-0854.2011.01302.x 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Journal Article
  ​ ​The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export​
  Waldmann, I.; Spillner, C. & Kehlenbach, R. H.​ (2012) 
  Journal of Cell Science, 125(1) pp. 144​-154​.​ DOI: https://doi.org/10.1242/jcs.090316 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Journal Article | 
  ​ ​Herpes Simplex Virus ICP27 Protein Directly Interacts with the Nuclear Pore Complex through Nup62, Inhibiting Host Nucleocytoplasmic Transport Pathways​
  Malik, P.; Tabarraei, A.; Kehlenbach, R. H.; Korfali, N.; Iwasawa, R.; Graham, S. V. & Schirmer, E. C.​ (2012) 
  Journal of Biological Chemistry, 287(15) pp. 12277​-12292​.​ DOI: https://doi.org/10.1074/jbc.M111.331777 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Journal Article
  ​ ​Several Phenylalanine-Glycine Motives in the Nucleoporin Nup214 Are Essential for Binding of the Nuclear Export Receptor CRM1​
  Roloff, S.; Spillner, C. & Kehlenbach, R. H.​ (2013) 
  Journal of Biological Chemistry, 288(6) pp. 3952​-3963​.​ DOI: https://doi.org/10.1074/jbc.M112.433243 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Journal Article | 
  ​ ​Post-transcriptional regulation of CD83 expression by AUF1 proteins​
  Ehlers, C.; Schirmer, S.; Kehlenbach, R. H.; Hauber, J. & Chemnitz, J.​ (2013) 
  Nucleic Acids Research, 41(1) pp. 206​-219​.​ DOI: https://doi.org/10.1093/nar/gks1069 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Journal Article
  ​ ​Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport​
  Snow, C. J.; Dar, A.; Dutta, A.; Kehlenbach, R. H. & Paschal, B. M.​ (2013) 
  The Journal of Cell Biology, 201(4) pp. 541​-557​.​ DOI: https://doi.org/10.1083/jcb.201212117 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Journal Article
  ​ ​Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry​
  Thakar, K.; Karaca, S.; Port, S. A.; Urlaub, H. & Kehlenbach, R. H.​ (2013) 
  Molecular & Cellular Proteomics, 12(3) pp. 664​-678​.​ DOI: https://doi.org/10.1074/mcp.M112.024877 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Review
  ​ ​Novel Approaches for the Identification of Nuclear Transport Receptor Substrates​
  Kimura, M.; Thakar, K.; Karaca, S.; Imamoto, N.& Kehlenbach, R. H.​ (2014)
  NUCLEAR PORE COMPLEXES AND NUCLEOCYTOPLASMIC TRANSPORT - METHODS pp. 353​-378​.​
  San diego​: Elsevier Academic Press Inc. DOI: https://doi.org/10.1016/B978-0-12-417160-2.00016-3 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article | 
  ​ ​Importin 7 and Nup358 Promote Nuclear Import of the Protein Component of Human Telomerase​
  Frohnert, C.; Hutten, S.; Waelde, S.; Nath, A. & Kehlenbach, R. H.​ (2014) 
  PLoS ONE, 9(2) art. e88887​.​ DOI: https://doi.org/10.1371/journal.pone.0088887 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Review
  ​ ​Analysis of Nucleocytoplasmic Transport in Digitonin-Permeabilized Cells Under Different Cellular Conditions​
  Furuta, M.; Kose, S.; Kehlenbach, R. H.& Imamoto, N.​ (2014)
  NUCLEAR PORE COMPLEXES AND NUCLEOCYTOPLASMIC TRANSPORT - METHODS pp. 331​-352​.​
  San diego​: Elsevier Academic Press Inc. DOI: https://doi.org/10.1016/B978-0-12-417160-2.00015-1 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article
  ​ ​Distinct functions of the dual leucine zipper kinase depending on its subcellular localization​
  Wallbach, M.; Escobar, J. D.; Babaeikelishomi, R.; Stahnke, M.-J.; Blume, R.; Schroeder, S. & Kruegel, J. et al.​ (2016) 
  Cellular Signalling, 28(4) pp. 272​-283​.​ DOI: https://doi.org/10.1016/j.cellsig.2016.01.002 
  ​Details  DOI  PMID  PMC  WoS 

• 2019 | Journal Article | Research Paper | 
  ​ ​Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.​
  Blenski, M. & Kehlenbach, R. H.​ (2019) 
  International Journal of Molecular Sciences, 20(2) art. 334​.​ DOI: https://doi.org/10.3390/ijms20020334 
  ​Details  DOI  PMID  PMC 

• 2020 | Journal Article
  ​ ​The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice​
  Lavau, C. P.; Aumann, W. K.; Sze, S. Sze, Sei-Gyung K.; Gupta, V.; Ripple, K.; Port, S. A. & Kehlenbach, R. H. et al.​ (2020) 
  PLoS One, 15(4) pp. e0232036​.​ DOI: https://doi.org/10.1371/journal.pone.0232036 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​A nuclear export sequence promotes CRM1-dependent targeting of the nucleoporin Nup214 to the nuclear pore complex​
  Hamed, M.; Caspar, B.; Port, S. A. & Kehlenbach, R. H.​ (2021) 
  Journal of Cell Science, 134(6).​ DOI: https://doi.org/10.1242/jcs.258095 
  ​Details  DOI 

• 2022 | Book Chapter
  ​ ​RAPIDS, a method for sub-compartmental identification of protein interactomes​
  James, C.; Lenz, C.& Kehlenbach, R. H.​ (2022)
  In: Integrated Methods in Protein Biochemistry: Part A pp. 109​-130. ​Elsevier. DOI: https://doi.org/10.1016/bs.mie.2022.07.006 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​CRM1 Promotes Capsid Disassembly and Nuclear Envelope Translocation of Adenovirus Independently of Its Export Function​
  Lagadec, F.; Carlon-Andres, I.; Ragues, J.; Port, S.; Wodrich, H. & Kehlenbach, R. H.​ (2022) 
  Journal of Virology, 96(3).​ DOI: https://doi.org/10.1128/jvi.01273-21 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein​
  Pörschke, M.; Rodríguez-González, I.; Parfentev, I.; Urlaub, H. & Kehlenbach, R. H.​ (2023) 
  Journal of Biological Chemistry, pp. 102932​.​ DOI: https://doi.org/10.1016/j.jbc.2023.102932 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Interaction of nucleoporins with nuclear transport receptors: a structural perspective​
  Kehlenbach, R. H.; Neumann, P.; Ficner, R. & Dickmanns, A.​ (2023) 
  Biological Chemistry,.​ DOI: https://doi.org/10.1515/hsz-2023-0155 
  ​Details  DOI 

Researcher

Sort

Items per Page