Author Han, Younghun

• 2012 | Journal Article
  ​ ​Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers​
  Hartz, S. M.; Short, S. E.; Saccone, N. L.; Culverhouse, R.; Chen, L.; Schwantes-An, T.-H. & Coon, H. et al.​ (2012) 
  Archives of General Psychiatry, 69(8) pp. 854​.​ DOI: https://doi.org/10.1001/archgenpsychiatry.2012.124 
  ​Details  DOI 

• 2012 | Conference Abstract
  ​ ​Application of the Empirical Hierarchical Bayes Approach for Gene-Environment Interaction to TRICL Lung Cancer GWAS​
  Sohns, M.; Viktorova, E.; Fehringer, G.; Gaborieau, V.; Han, Y.; Chang-Claude, J. & Heinrich, J. et al.​ (2012)
  Genetic Epidemiology, 36(7) ​Annual Meeting of the International-Genetic-Epidemiology-Society (IGES)​, Stevenson, WA.
  Hoboken​: Wiley-blackwell.
  ​Details  WoS 

• 2012 | Journal Article | 
  ​ ​Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls​
  Timofeeva, M. N.; Hung, R. J.; Rafnar, T.; Christiani, D. C.; Field, J. K.; Bickeboeller, H.   & Risch, A. et al.​ (2012) 
  Human Molecular Genetics, 21(22) pp. 4980​-4995​.​ DOI: https://doi.org/10.1093/hmg/dds334 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Journal Article
  ​ ​Empirical Hierarchical Bayes Approach to Gene-Environment Interactions: Development and Application to Genome-Wide Association Studies of Lung Cancer in TRICL​
  Sohns, M.; Viktorova, E.; Amos, C. I.; Brennan, P. C.; Fehringer, G.; Gaborieau, V. & Han, Y. et al.​ (2013) 
  Genetic Epidemiology, 37(6) pp. 551​-559​.​ DOI: https://doi.org/10.1002/gepi.21741 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article | 
  ​ ​Pleiotropic Associations of Risk Variants Identified for Other Cancers With Lung Cancer Risk: The PAGE and TRICL Consortia​
  Park, S. L.; Fesinmeyer, M. D.; Timofeeva, M. N.; Caberto, C. P.; Kocarnik, J. M.; Han, Y. & Love, S.-A. et al.​ (2014) 
  JNCI Journal of the National Cancer Institute, 106(4) art. dju061​.​ DOI: https://doi.org/10.1093/jnci/dju061 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Review
  ​ ​CHRNA5 Risk Variant Predicts Delayed Smoking Cessation and Earlier Lung Cancer Diagnosis-A Meta-Analysis​
  Chen, L.-S.; Hung, R. J.; Baker, T.; Horton, A.; Culverhouse, R.; Saccone, N.& Cheng, I. et al.​ (2015)
  JNCI Journal of the National Cancer Institute, 107​(5).​
  Oxford Univ Press Inc. DOI: https://doi.org/10.1093/jnci/djv100 
  ​Details  DOI  WoS 

• 2015 | Journal Article
  ​ ​Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions​
  Qian, D. C.; Byun, J.; Han, Y.; Greene, C. S.; Field, J. K.; Hung, R. J. & Brhane, Y. et al.​ (2015) 
  Human Molecular Genetics, 24(25) pp. 7406​-7420​.​ DOI: https://doi.org/10.1093/hmg/ddv440 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Conference Paper
  ​ ​Abstract 2569: A genome wide association study of lung cancer identifies 11 novel susceptibility loci​
  Mckay, J. D.; Li, Y.; Han, Y.; Xioa, X.; Field, J.; Zong, X. & Bickeböller, H.  et al.​ (2016)
  pp. 2569​-2569. ​Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA​
  American Association for Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2016-2569 
  ​Details  DOI 

• 2016 | Journal Article
  ​ ​Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis​
  Chen, L.-S.; Baker, T.; Hung, R. J.; Horton, A.; Culverhouse, R.; Hartz, S. & Saccone, N. et al.​ (2016) 
  EBioMedicine, 11 pp. 219​-226​.​ DOI: https://doi.org/10.1016/j.ebiom.2016.08.012 
  ​Details  DOI 

• 2016 | Journal Article
  ​ ​Pleiotropic Analysis of Lung Cancer and Blood Triglycerides​
  Zuber, V.; Marconett, C. N.; Shi, J.; Hua, X.; Wheeler, W.; Yang, C. & Song, L. et al.​ (2016) 
  JNCI Journal of the National Cancer Institute, 108(12) art. djw167​.​ DOI: https://doi.org/10.1093/jnci/djw167 
  ​Details  DOI  WoS 

• 2016 | Journal Article | 
  ​ ​A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer​
  Yuan, H.; Liu, H.; Liu, Z.; Owzar, K.; Han, Y.; Su, L. I. & Wei, Y. et al.​ (2016) 
  Scientific Reports, 6 art. 34234​.​ DOI: https://doi.org/10.1038/srep34234 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article
  ​ ​Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14 463 cases and 44 188 controls​
  Kang, X.; Liu, H.; Onaitis, M. W.; Liu, Z.; Owzar, K.; Han, Y. & Su, L. I. et al.​ (2016) 
  Carcinogenesis, 37(3) pp. 280​-289​.​ DOI: https://doi.org/10.1093/carcin/bgw014 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article
  ​ ​Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk​
  Patel, Y. M.; Park, S. L.; Han, Y.; Wilkens, L. R.; Bickeböller, H. ; Rosenberger, A.   & Caporaso, N. et al.​ (2016) 
  Cancer Research, 76(19) pp. 5768​-5776​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-16-0446 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer​
  Feng, Y.; Wang, Y.; Liu, H.; Liu, Z.; Mills, C.; Owzar, K. & Xie, J. et al.​ (2017) 
  Molecular Carcinogenesis, 57(2) pp. 216​-224​.​ DOI: https://doi.org/10.1002/mc.22748 
  ​Details  DOI 

• 2017 | Journal Article
  ​ ​Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population​
  Li, Y.; Xiao, X.; Han, Y.; Gorlova, O.; Qian, D.; Leighl, N. & Johansen, J. S et al.​ (2017) 
  Carcinogenesis, 39(3) pp. 336​-346​.​ DOI: https://doi.org/10.1093/carcin/bgx113 
  ​Details  DOI 

• 2017 | Journal Article
  ​ ​Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes​
  McKay, J. D; Hung, R. J; Han, Y.; Zong, X.; Carreras-Torres, R.; Christiani, D. C & Caporaso, N. E et al.​ (2017) 
  Nature Genetics, 49(7) pp. 1126​-1132​.​ DOI: https://doi.org/10.1038/ng.3892 
  ​Details  DOI 

• 2017 | Journal Article | 
  ​ ​Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium​
  Feng, Y.; Wang, Y.; Liu, H.; Liu, Z.; Mills, C.; Han, Y. & Hung, R. J. et al.​ (2017) 
  Scientific Reports, 7 art. 825​.​ DOI: https://doi.org/10.1038/s41598-017-00850-0 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus​
  Yin, J.; Liu, H.; Liu, Z.; Owzar, K.; Han, Y.; Su, L. I. & Wei, Y. et al.​ (2017) 
  Molecular Carcinogenesis, 56(6) pp. 1663​-1672​.​ DOI: https://doi.org/10.1002/mc.22622 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​Susceptibility Loci of CNOT6 in the General mRNA Degradation Pathway and Lung Cancer Risk-A Re-Analysis of Eight GWASs​
  Zhou, F.; Wang, Y.; Liu, H.; Ready, N.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2017) 
  Molecular Carcinogenesis, 56(4) pp. 1227​-1238​.​ DOI: https://doi.org/10.1002/mc.22585 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​Functional variants in DCAF4 associated with lung cancer risk in European populations​
  Liu, H.; Liu, Z.; Wang, Y.; Stinchcombe, T. E.; Owzar, K.; Han, Y. & Hung, R. J. et al.​ (2017) 
  Carcinogenesis, 38(5) pp. 541​-551​.​ DOI: https://doi.org/10.1093/carcin/bgx033 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article | 
  ​ ​Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs​
  Pan, Y.; Liu, H.; Wang, Y.; Kang, X.; Liu, Z.; Owzar, K. & Han, Y. et al.​ (2017) 
  Scientific Reports, 7 art. 44634​.​ DOI: https://doi.org/10.1038/srep44634 
  ​Details  DOI  PMID  PMC  WoS 

• 2018 | Journal Article | 
  ​ ​Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity​
  Ferreiro-Iglesias, A.; Lesseur, C.; McKay, J.; Hung, R. J.; Han, Y.; Zong, X. & Christiani, D. et al.​ (2018) 
  Nature Communications, 9(1).​ DOI: https://doi.org/10.1038/s41467-018-05890-2 
  ​Details  DOI 

• 2019 | Journal Article | 
  ​ ​Publisher Correction: Shared heritability and functional enrichment across six solid cancers​
  Jiang, X.; Finucane, H. K.; Schumacher, F. R.; Schmit, S. L.; Tyrer, J. P.; Han, Y. & Michailidou, K. et al.​ (2019) 
  Nature Communications, 10(1).​ DOI: https://doi.org/10.1038/s41467-019-12095-8 
  ​Details  DOI 

• 2019 | Journal Article
  ​ ​Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development​
  Li, Y.; Xiao, X.; Bossé, Y.; Gorlova, O.; Gorlov, I.; Han, Y. & Byun, J. et al.​ (2019) 
  Oncotarget, 10(19) pp. 1760​-1774​.​ DOI: https://doi.org/10.18632/oncotarget.26678 
  ​Details  DOI 

• 2019 | Journal Article | 
  ​ ​Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region​
  Hung, R. J.; Spitz, M. R.; Houlston, R. S.; Schwartz, A. G.; Field, J. K.; Ying, J. & Li, Y. et al.​ (2019) 
  Journal of Thoracic Oncology, 14(8) pp. 1360​-1369​.​ DOI: https://doi.org/10.1016/j.jtho.2019.04.008 
  ​Details  DOI  PMID  PMC 

• 2019 | Journal Article | 
  ​ ​Shared heritability and functional enrichment across six solid cancers​
  Jiang, X.; Finucane, H. K.; Schumacher, F. R.; Schmit, S. L.; Tyrer, J. P.; Han, Y. & Michailidou, K. et al.​ (2019) 
  Nature Communications, 10(1) art. 431​.​ DOI: https://doi.org/10.1038/s41467-018-08054-4 
  ​Details  DOI  PMID  PMC 

• 2019 | Journal Article
  ​ ​Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis​
  Zhu, Y.; Wei, Y.; Zhang, R.; Dong, X.; Shen, S.; Zhao, Y. & Bai, J. et al.​ (2019) 
  Cancer Epidemiology, Biomarkers & Prevention, 28(5) pp. 935​-942​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-18-0356 
  ​Details  DOI  PMID  PMC 

• 2020 | Journal Article | 
  ​ ​Protein-altering germline mutations implicate novel genes related to lung cancer development​
  Ji, X.; Mukherjee, S.; Landi, M. T.; Bosse, Y.; Joubert, P.; Zhu, D. & Gorlov, I. et al.​ (2020) 
  Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-020-15905-6 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer​
  Byun, J.; Han, Y.; Li, Y.; Xia, J.; Long, E.; Choi, J. & Xiao, X. et al.​ (2022) 
  Nature Genetics, 54(8) pp. 1167​-1177​.​ DOI: https://doi.org/10.1038/s41588-022-01115-x 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk​
  Yang, W.; Liu, H.; Zhang, R.; Freedman, J. A.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2022) 
  npj Precision Oncology, 6(1).​ DOI: https://doi.org/10.1038/s41698-022-00281-9 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis​
  Cheng, C.; Hong, W.; Li, Y.; Xiao, X.; McKay, J.; Han, Y. & Byun, J. et al.​ (2023) 
  Journal of Thoracic Oncology,.​ DOI: https://doi.org/10.1016/j.jtho.2023.05.001 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies​
  Li, Y.; Xiao, X.; Li, J.; Han, Y.; Cheng, C.; Fernandes, G. F. & Slewitzke, S. E. et al.​ (2024) 
  Cancer Epidemiology, Biomarkers & Prevention, pp. OF1​-OF11​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-23-0613 
  ​Details  DOI 

Researcher

Sort

Items per Page