Autor Spang, Rainer

• 2006 | Zeitschriftenartikel
  ​ ​A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling​
  Hummel, M.; Bentink, S.; Berger, H.; Klapper, W.; Wessendorf, S.; Barth, T. F. E. & Bernd, H. W. u.a.​ (2006) 
  New England Journal of Medicine, 354(23) pp. 2419​-2430​.​ DOI: https://doi.org/10.1056/NEJMoa055351 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Konferenzbeitrag (Abstract)
  ​ ​Conserved oncogenic module activation patterns (COMAPS) identify biologically homogeneous groups of diffuse large B-cell lymphomas and clearly define Burkitt lymphoma​
  Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. u.a.​ (2008)
  Annals of Oncology, 19 ​10th International Conference on Malignant Lymphoma​, Lugano, SWITZERLAND.
  Oxford​: Oxford Univ Press.
  ​Details  WoS 

• 2008 | Konferenzbeitrag (Abstract)
  ​ ​Different subtypes of aggressive B cell lymphomas share an epigenetic signature enriched for polycomb targets in stem cells​
  Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Klapper, W.; Wickham-Garcia, E. & Rosolowski, M. u.a.​ (2008)
  Annals of Oncology, 19 ​10th International Conference on Malignant Lymphoma​, Lugano, SWITZERLAND.
  Oxford​: Oxford Univ Press.
  ​Details  WoS 

• 2008 | Zeitschriftenartikel
  ​ ​Pathway activation patterns in diffuse large B-cell lymphomas​
  Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. u.a.​ (2008) 
  Leukemia, 22(9) pp. 1746​-1754​.​ DOI: https://doi.org/10.1038/leu.2008.166 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Zeitschriftenartikel
  ​ ​Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials​
  Klapper, W.; Szczepanowski, M.; Burkhardt, B.; Berger, H.; Rosolowski, M.; Bentink, S. & Schwaenen, C. u.a.​ (2008) 
  Blood, 112(4) pp. 1374​-1381​.​ DOI: https://doi.org/10.1182/blood-2008-01-136465 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Zeitschriftenartikel
  ​ ​Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma​
  Dierlamm, J.; Penas, E. M. M.; Bentink, S.; Wessendorf, S.; Berger, H.; Hummel, M. & Klapper, W. u.a.​ (2008) 
  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 93(5) pp. 688​-696​.​ DOI: https://doi.org/10.3324/haematol.12057 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Zeitschriftenartikel
  ​ ​Analyzing gene perturbation screens with nested effects models in R and bioconductor​
  Fröhlich, H.; Beißbarth, T. ; Tresch, A.; Kostka, D.; Jacob, J.; Spang, R. & Markowetz, F.​ (2008) 
  Bioinformatics, 24(21) pp. 2549​-2550​.​ DOI: https://doi.org/10.1093/bioinformatics/btn446 
  ​Details  DOI  PMID  PMC 

• 2009 | Zeitschriftenartikel
  ​ ​Microarray-Based Genomic Profiling Reveals Novel Genomic Aberrations in Follicular War Lymphoma Which Associate with Patient Survival and Gene Expression Status​
  Schwaenen, C.; Viardot, A.; Berger, H.; Barth, T. F. E.; Bentink, S.; Doehner, H. & Enz, M. u.a.​ (2009) 
  Genes Chromosomes and Cancer, 48(1) pp. 39​-54​.​ DOI: https://doi.org/10.1002/gcc.20617 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Zeitschriftenartikel
  ​ ​New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling​
  Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Ammerpohl, O.; Wickham-Garcia, E. & Rosolowski, M. u.a.​ (2009) 
  Blood, 113(11) pp. 2488​-2497​.​ DOI: https://doi.org/10.1182/blood-2008-04-152900 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Konferenzbeitrag (Abstract)
  ​ ​A c-Myc induced gene expression signature in human germinal center B cells predicts subtypes of aggressive non-Hodgkin Lymphoma​
  Schrader, A.; Bentink, S.; Spang, R.; Lenze, D.; Hummel, M.; Kuo, M. & Murray, P. u.a.​ (2010)
  EJC SUPPLEMENTS, 8(5) ​21st Meeting of the European-Association-for-Cancer-Research​, Oslo, NORWAY.
  Oxford​: Pergamon-elsevier Science Ltd.
  ​Details  WoS 

• 2010 | Zeitschriftenartikel | 
  ​ ​Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis​
  Scholtysik, R.; Kreuz, M.; Klapper, W.; Burkhardt, B.; Feller, A. C.; Hummel, M. & Loeffler, M. u.a.​ (2010) 
  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(12) pp. 2047​-2055​.​ DOI: https://doi.org/10.3324/haematol.2010.026831 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Zeitschriftenartikel
  ​ ​Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults​
  Salaverria, I.; Philipp, C.; Oschlies, I.; Kohler, C. W.; Kreuz, M.; Szczepanowski, M. & Burkhardt, B. u.a.​ (2011) 
  Blood, 118(1) pp. 139​-147​.​ DOI: https://doi.org/10.1182/blood-2011-01-330795 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Zeitschriftenartikel
  ​ ​Genomic data integration using guided clustering​
  Maneck, M.; Schrader, A.; Kube, D. & Spang, R.​ (2011) 
  Bioinformatics, 27(16) pp. 2231​-2238​.​ DOI: https://doi.org/10.1093/bioinformatics/btr363 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Konferenzbeitrag (Abstract)
  ​ ​SOCS1 Mutation Subtypes Predict Divergent Outcomes in DLBCL Patients​
  Lennerz, J. K.; Schif, B.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Truemper, L. H. u.a.​ (2012)
  Blood, 120(21) ​54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)​, Atlanta, GA.
  Washington​: Amer Soc Hematology.
  ​Details  WoS 

• 2012 | Zeitschriftenartikel
  ​ ​Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing​
  Richter, J.; Schlesner, M.; Hoffmann, S.; Kreuz, M.; Leich, E.; Burkhardt, B. & Rosolowski, M. u.a.​ (2012) 
  Nature Genetics, 44(12) pp. 1316​-1320​.​ DOI: https://doi.org/10.1038/ng.2469 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Zeitschriftenartikel
  ​ ​T cells become licensed in the lung to enter the central nervous system​
  Odoardi, F. ; Sie, C.; Streyl, K.; Ulaganathan, V. K.; Schlaeger, C.; Lodygin, D. & Heckelsmiller, K. u.a.​ (2012) 
  Nature, 488(7413) pp. 675​.​ DOI: https://doi.org/10.1038/nature11337 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Zeitschriftenartikel
  ​ ​High myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas​
  Schrader, A.; Bentink, S.; Spang, R.; Lenze, D.; Hummel, M.; Kuo, M. & Arrand, J. R. u.a.​ (2012) 
  International Journal of Cancer, 131(4) pp. E348​-E361​.​ DOI: https://doi.org/10.1002/ijc.26423 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Zeitschriftenartikel
  ​ ​Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma​
  Klapper, W.; Kreuz, M.; Kohler, C. W.; Burkhardt, B.; Szczepanowski, M.; Salaverria, I. & Hummel, M. u.a.​ (2012) 
  Blood, 119(8) pp. 1882​-1887​.​ DOI: https://doi.org/10.1182/blood-2011-10-388470 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Zeitschriftenartikel | 
  ​ ​SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients.​
  Schif, B.; Lennerz, J. K.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Ritz, O. u.a.​ (2013) 
  Oncotarget, 4(1) pp. 35​-47​.​
  ​Details  PMID  PMC 

• 2014 | Zeitschriftenartikel | 
  ​ ​Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma​
  Aukema, S. M.; Kreuz, M.; Kohler, C. W.; Rosolowski, M.; Hasenclever, D.; Hummel, M. & Kueppers, R. u.a.​ (2014) 
  Haematologica, 99(4) pp. 726​-735​.​ DOI: https://doi.org/10.3324/haematol.2013.091827 
  ​Details  DOI  PMID  PMC  WoS 

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